Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions
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* Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America. | * Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.<ref name="AozasaTakakuwa20083">{{cite journal|last1=Aozasa|first1=Katsuyuki|last2=Takakuwa|first2=Tetsuya|last3=Hongyo|first3=Tadashi|last4=Yang|first4=Woo-Ick|title=Nasal NK/T-cell lymphoma: epidemiology and pathogenesis|journal=International Journal of Hematology|volume=87|issue=2|year=2008|pages=110–117|issn=0925-5710|doi=10.1007/s12185-008-0021-7}}</ref> | ||
* Nk cell lymphoma is usually associated with Epstein-Barr virus infection. | * Nk cell lymphoma is usually associated with Epstein-Barr virus infection. | ||
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=== Region === | === Region === | ||
*NK T cell lymphoma, nasal type (NNKTL) consist 3-10% of non-Hodgkin lymphoma in Asia and South America and less than 1% in Western countries. | *NK T cell lymphoma, nasal type (NNKTL) consist 3-10% of non-Hodgkin lymphoma in Asia and South America and less than 1% in Western countries. | ||
*It is estimated the incidence of NNKTL is higher in Asia by 10-folds. | *It is estimated the incidence of NNKTL is higher in Asia by 10-folds. | ||
=== Age === | === Age === | ||
* The median age of onset is approximately 50 years and it is common in elderly. | * The median age of onset is approximately 50 years and it is common in elderly. | ||
* Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease. | * Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease. | ||
Revision as of 14:19, 22 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
Epidemiology and Demographics
Mortality rate
- NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.
Race
- Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.[1]
- Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
Gender
- Extranodal NK/T-cell lymphoma shows male preponderance.
Region
- NK T cell lymphoma, nasal type (NNKTL) consist 3-10% of non-Hodgkin lymphoma in Asia and South America and less than 1% in Western countries.
- It is estimated the incidence of NNKTL is higher in Asia by 10-folds.
Age
- The median age of onset is approximately 50 years and it is common in elderly.
- Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease.
References
- ↑ Aozasa, Katsuyuki; Takakuwa, Tetsuya; Hongyo, Tadashi; Yang, Woo-Ick (2008). "Nasal NK/T-cell lymphoma: epidemiology and pathogenesis". International Journal of Hematology. 87 (2): 110–117. doi:10.1007/s12185-008-0021-7. ISSN 0925-5710.