Hepatopulmonary syndrome classification: Difference between revisions
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==Classification== | ==Classification== | ||
There is no established system for the classification of hepatopulmonary syndrome (HPS). | There is no established system for the classification of hepatopulmonary syndrome (HPS).<ref name="pmid18509123">Rodríguez-Roisin R, Krowka MJ (2008) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=18509123 Hepatopulmonary syndrome--a liver-induced lung vascular disorder.] ''N Engl J Med'' 358 (22):2378-87. [http://dx.doi.org/10.1056/NEJMra0707185 DOI:10.1056/NEJMra0707185] PMID: [https://pubmed.gov/18509123 18509123]</ref> | ||
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* Moderate: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen <math>\geq</math> 60 up to 80mmHg. | * Moderate: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen <math>\geq</math> 60 up to 80mmHg. | ||
* Severe: Alveolar-arterial oxygen gradient <math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 50 up to 60mmHg. | * Severe: Alveolar-arterial oxygen gradient <math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 50 up to 60mmHg. | ||
* Very severe: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen below 50 mmHg (< 300mmHg while the patient is breathing 100% oxygen). | * Very severe: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen below 50 mmHg (< 300mmHg while the patient is breathing 100% oxygen).<ref name="pmid27326810">Krowka MJ, Fallon MB, Kawut SM, Fuhrmann V, Heimbach JK, Ramsay MA et al. (2016) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=27326810 International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension.] ''Transplantation'' 100 (7):1440-52. [http://dx.doi.org/10.1097/TP.0000000000001229 DOI:10.1097/TP.0000000000001229] PMID: [https://pubmed.gov/27326810 27326810]</ref> | ||
==References== | ==References== |
Revision as of 13:39, 5 September 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
There is no established system for the classification of hepatopulmonary syndrome.
Classification
There is no established system for the classification of hepatopulmonary syndrome (HPS).[1]
HPS can be classified in term of severity based on atrial blood gas analysis, as follows:
- Mild: Alveolar-arterial oxygen gradient above, or equal to<math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 80mmHg.
- Moderate: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen <math>\geq</math> 60 up to 80mmHg.
- Severe: Alveolar-arterial oxygen gradient <math>\geq</math> 15mmHg, partial pressure of oxygen <math>\geq</math> 50 up to 60mmHg.
- Very severe: Alveolar-arterial oxygen gradient <math>\geq</math>15mmHg, partial pressure of oxygen below 50 mmHg (< 300mmHg while the patient is breathing 100% oxygen).[2]
References
- ↑ Rodríguez-Roisin R, Krowka MJ (2008) Hepatopulmonary syndrome--a liver-induced lung vascular disorder. N Engl J Med 358 (22):2378-87. DOI:10.1056/NEJMra0707185 PMID: 18509123
- ↑ Krowka MJ, Fallon MB, Kawut SM, Fuhrmann V, Heimbach JK, Ramsay MA et al. (2016) International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension. Transplantation 100 (7):1440-52. DOI:10.1097/TP.0000000000001229 PMID: 27326810