Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions
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=== Mortality rate === | === Mortality rate === | ||
* NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[Metastasis - brain|metastasis]] | * NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[Metastasis - brain|metastasis]]. | ||
=== Age === | === Age === | ||
* The [[median]] age of onset is approximately 50 years and it is common in elderly. | * The [[median]] age of onset is approximately 50 years and it is common in elderly<ref name="pmid12876666">{{cite journal| author=Jaffe ES, Krenacs L, Raffeld M| title=Classification of cytotoxic T-cell and natural killer cell lymphomas. | journal=Semin Hematol | year= 2003 | volume= 40 | issue= 3 | pages= 175-84 | pmid=12876666 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12876666 }}</ref>. | ||
*[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[Epstein Barr virus|EBV]]-associated disease. | *[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[Epstein Barr virus|EBV]]-associated disease. | ||
Revision as of 13:52, 2 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.The median age of onset is approximately 50 years and it is common in elderly. extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.Natural Killer (NK) cell lymphoma is a rare disease. extranodal NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries
Epidemiology and Demographics
Mortality rate
- NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.
Age
- The median age of onset is approximately 50 years and it is common in elderly[1].
- Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.
Race
- Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.
- Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
Gender
- Extranodal NK/T-cell lymphoma shows male preponderance.
Region
- Extranodal NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries.
- It is estimated the incidence of NNKTL is higher in Asia by 10-folds.
References
- ↑ Jaffe ES, Krenacs L, Raffeld M (2003). "Classification of cytotoxic T-cell and natural killer cell lymphomas". Semin Hematol. 40 (3): 175–84. PMID 12876666.