Osteosarcoma classification: Difference between revisions
Jump to navigation
Jump to search
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
[[Osteosarcoma]] (OS) is a rare bone cancer which affects both adolescents and young adults. Osteosarcoma was classified as primary and secondary. Later the the [[World Health Organization]] sub-typed as intramedullary/central and surface osteosarcoma with a number of sub-types under each group. | [[Osteosarcoma]] (OS) is a rare [[bone cancer]] which affects both adolescents and young adults. [[Osteosarcoma]] was classified as primary and secondary. Later the the [[World Health Organization]] sub-typed as [[intramedullary]]/[[central]] and surface [[osteosarcoma]] with a number of sub-types under each group. | ||
==Classification == | ==Classification == | ||
| Line 15: | Line 15: | ||
{| class="wikitable" | {| class="wikitable" | ||
|+Classification of osteosarcoma | |+Classification of osteosarcoma | ||
|Primary osteosarcoma | | | ||
|Conventional-intramedullary/central high grade (most common) further sub-typed as: | * Primary osteosarcoma | ||
|Osteoblastic (50 | | | ||
* [[Conventional osteosarcoma|Conventional]]-[[intramedullary]]/central high grade (most common) further sub-typed as: | |||
| | |||
* [[Osteoblastic osteosarcoma|Osteoblastic]] (50%) | |||
Fibroblastic (25%) | * [[Chondroblast|Chondroblastic]] (25%) | ||
* [[Fibroblastic]] (25%) | |||
|- | |- | ||
|Secondary osteosracomas | | | ||
|Unusual forms of osteosarcoma given below are viewed as subtypes of conventional osteosarcoma because their biological behavior is similar. | * Secondary osteosracomas | ||
|Osteoblastic osteosarcoma-sclerosing type | | | ||
Osteosarcoma resembling | * Unusual forms of [[osteosarcoma]] given below are viewed as subtypes of conventional [[osteosarcoma]] because their biological behavior is similar. | ||
| | |||
Chondromyxoid fibroma‑like osteosarcoma | * Osteoblastic osteosarcoma-sclerosing type | ||
* Osteosarcoma resembling [[osteosarcoma]] | |||
Chondroblastoma-like osteosarcoma | * [[Chondromyxoid fibroma|Chondromyxoid]] fibroma‑like osteosarcoma | ||
* [[Chondroblastoma]]-like osteosarcoma | |||
Clear-cell osteosarcoma | * [[Clear cell tumor|Clear-cell osteosarcoma]] | ||
* [[Malignant]] fibrous [[histiocytoma]]‑like osteosarcoma | |||
Malignant fibrous | * [[Giant cell]] rich [[osteosarcoma]]-[[Epithelioid]] [[osteosarcoma]] | ||
Giant cell rich osteosarcoma Epithelioid osteosarcoma | |||
|} | |} | ||
Revision as of 13:30, 10 October 2019
|
Osteosarcoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Osteosarcoma classification On the Web |
|
American Roentgen Ray Society Images of Osteosarcoma classification |
|
Risk calculators and risk factors for Osteosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
Overview
Osteosarcoma (OS) is a rare bone cancer which affects both adolescents and young adults. Osteosarcoma was classified as primary and secondary. Later the the World Health Organization sub-typed as intramedullary/central and surface osteosarcoma with a number of sub-types under each group.
Classification
- Osteosarcoma (OS) may be classified into several subtypes based on World Health Organization and are as follows:[1][2][3][4][4][5][1][6][7]
|
|
|
|
|
|
| subtypes | Osteosarcoma |
|---|---|
| CENTRAL (MEDULLARY) | a. Conventional high-grade central osteosarcoma (80%)
b. Telangiectatic osteosarcoma (4%) c. Intraosseous well-differentiated (low-grade) osteosarcoma (1-2%) d. Small cell osteosarcoma (1-2%) |
| SURFACE (PERIPHERAL) | a. Parosteal (juxtacortical) well-differentiated (low-grade) osteosarcoma (4-6%)
b. Periosteal osteosarcoma - low- to intermediate-grade osteosarcoma (<4%) c. High-grade surface osteosarcoma (1%) |
References
- ↑ 1.0 1.1 Duong LM, Richardson LC (2013). "Descriptive epidemiology of malignant primary osteosarcoma using population-based registries, United States, 1999-2008". J Registry Manag. 40 (2): 59–64. PMC 4476493. PMID 24002129.
- ↑ Bielack SS, Hecker-Nolting S, Blattmann C, Kager L (2016). "Advances in the management of osteosarcoma". F1000Res. 5: 2767. doi:10.12688/f1000research.9465.1. PMC 5130082. PMID 27990273.
- ↑ Kundu ZS (May 2014). "Classification, imaging, biopsy and staging of osteosarcoma". Indian J Orthop. 48 (3): 238–46. doi:10.4103/0019-5413.132491. PMC 4052020. PMID 24932027.
- ↑ 4.0 4.1 Misaghi A, Goldin A, Awad M, Kulidjian AA (2018). "Osteosarcoma: a comprehensive review". SICOT J. 4: 12. doi:10.1051/sicotj/2017028. PMC 5890448. PMID 29629690.
- ↑ Ozaki T, Flege S, Liljenqvist U, Hillmann A, Delling G, Salzer-Kuntschik M, Jürgens H, Kotz R, Winkelmann W, Bielack SS (February 2002). "Osteosarcoma of the spine: experience of the Cooperative Osteosarcoma Study Group". Cancer. 94 (4): 1069–77. PMID 11920477.
- ↑ Hamre MR, Severson RK, Chuba P, Lucas DR, Thomas RL, Mott MP (December 2002). "Osteosarcoma as a second malignant neoplasm". Radiother Oncol. 65 (3): 153–7. PMID 12464443.
- ↑ Barker JP, Monument MJ, Jones KB, Putnam AR, Randall RL (May 2015). "Secondary osteosarcoma: is there a predilection for the chondroblastic subtype?". Orthopedics. 38 (5): e359–66. doi:10.3928/01477447-20150504-51. PMID 25970361.