Pineocytoma natural history, complications and prognosis: Difference between revisions
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Homa Najafi (talk | contribs) Created page with "__NOTOC__ {{Pineocytoma}} {{CMG}}{{AE}}{{SR}}{{Homa}} ==Overview== If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifes..." |
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*[Subtype of disease/malignancy] is associated with the most favorable prognosis. | *[Subtype of disease/malignancy] is associated with the most favorable prognosis. | ||
*The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis. | *The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis. | ||
==Natural History, Complication and Prognosis== | |||
===Natural History=== | |||
If left untreated, patients with pineocytoma may progress to develop seizures, [[obstructive hydrocephalus]], local recurrence, and [[CSF]] metastasis.<ref name="symptoms1">Clinical presentation of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineocytoma. Accessed on November 20, 2015</ref><ref name="prog1">Treatment and prognosis of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015.http://radiopaedia.org/articles/pineocytoma. Accessed on November 20, 2015</ref> | |||
===Complications=== | |||
Common complications of pineocytoma include:<ref name="prog1">Treatment and prognosis of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015.http://radiopaedia.org/articles/pineocytoma. Accessed on November 20, 2015</ref><ref name="HiratoNakazato2001">{{cite journal|last1=Hirato|first1=Junko|last2=Nakazato|first2=Yoichi|journal=Journal of Neuro-Oncology|volume=54|issue=3|year=2001|pages=239–249|issn=0167594X|doi=10.1023/A:1012721723387}}</ref> | |||
*[[Obstructive hydrocephalus]] | |||
*Local recurrence | |||
*[[CSF|CSF metastasis]] | |||
*[[metastasis|Distant metastasis]] (most commonly, [[lung]]) | |||
===Prognosis=== | |||
*Prognosis is generally excellent, and the 5-year survival rate of patients with pineocytoma is approximately 86%.<ref name="prog1">Treatment and prognosis of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineocytoma. Accessed on November 20, 2015</ref> | |||
*Pineocytoma has the most favorable prognosis among all the pineal gland tumors.<ref name="DeshmukhSmith2004">{{cite journal|last1=Deshmukh|first1=Vivek R.|last2=Smith|first2=Kris A.|last3=Rekate|first3=Harold L.|last4=Coons|first4=Stephen|last5=Spetzler|first5=Robert F.|title=Diagnosis and Management of Pineocytomas|journal=Neurosurgery|volume=55|issue=2|year=2004|pages=349–357|issn=0148-396X|doi=10.1227/01.NEU.0000129479.70696.D2}}</ref> | |||
*Clark et al. after performing a systematic review of the literature reported that the 1- and 5-year progression free survival (PFS) rates for patients that underwent resection versus the biopsy group were 97% and 90%, and 89% and 75% respectively. The 1- and 5-year PFS rates for the gross total resection group versus the group undergoing subtotal resection combined with radiation therapy were 100% and 94%, and 100% and 84% respectively.<ref name="Alexiou2012">{{cite journal|last1=Alexiou|first1=George A|title=Management of pineal region tumours in children|journal=Journal of Solid Tumors|volume=2|issue=2|year=2012|issn=1925-4075|doi=10.5430/jst.v2n2p15}}</ref> | |||
==References== | ==References== | ||
Latest revision as of 15:14, 10 October 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2] Homa Najafi, M.D.[3]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of [disease name] include:
- [Complication 1]
- [Complication 2]
- [Complication 3]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
- Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
Natural History, Complication and Prognosis
Natural History
If left untreated, patients with pineocytoma may progress to develop seizures, obstructive hydrocephalus, local recurrence, and CSF metastasis.[1][2]
Complications
Common complications of pineocytoma include:[2][3]
- Obstructive hydrocephalus
- Local recurrence
- CSF metastasis
- Distant metastasis (most commonly, lung)
Prognosis
- Prognosis is generally excellent, and the 5-year survival rate of patients with pineocytoma is approximately 86%.[2]
- Pineocytoma has the most favorable prognosis among all the pineal gland tumors.[4]
- Clark et al. after performing a systematic review of the literature reported that the 1- and 5-year progression free survival (PFS) rates for patients that underwent resection versus the biopsy group were 97% and 90%, and 89% and 75% respectively. The 1- and 5-year PFS rates for the gross total resection group versus the group undergoing subtotal resection combined with radiation therapy were 100% and 94%, and 100% and 84% respectively.[5]
References
- ↑ Clinical presentation of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineocytoma. Accessed on November 20, 2015
- ↑ 2.0 2.1 2.2 Treatment and prognosis of pineocytoma. Dr Bruno Di Muzio and Dr Frank Gaillard et al. Radiopaedia 2015.http://radiopaedia.org/articles/pineocytoma. Accessed on November 20, 2015
- ↑ Hirato, Junko; Nakazato, Yoichi (2001). Journal of Neuro-Oncology. 54 (3): 239–249. doi:10.1023/A:1012721723387. ISSN 0167-594X. Missing or empty
|title=(help) - ↑ Deshmukh, Vivek R.; Smith, Kris A.; Rekate, Harold L.; Coons, Stephen; Spetzler, Robert F. (2004). "Diagnosis and Management of Pineocytomas". Neurosurgery. 55 (2): 349–357. doi:10.1227/01.NEU.0000129479.70696.D2. ISSN 0148-396X.
- ↑ Alexiou, George A (2012). "Management of pineal region tumours in children". Journal of Solid Tumors. 2 (2). doi:10.5430/jst.v2n2p15. ISSN 1925-4075.