Myxoma laboratory tests: Difference between revisions
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===Blood tests=== | ===Blood tests=== | ||
There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional symptoms are associated with the following blood count (CBC) findings:<ref name="pmid24599357">{{cite journal |vauthors=Hartig I, Kraatz EG, Beurich HW, Moosig F |title=[Atrial myxoma with clinical signs of systemic inflammatory disease.] |journal=Z Rheumatol |volume= |issue= |pages= |year=2014 |pmid=24599357 |doi=10.1007/s00393-013-1347-y |url=}}</ref> | There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional symptoms are associated with the following cell blood count (CBC) findings:<ref name="pmid24599357">{{cite journal |vauthors=Hartig I, Kraatz EG, Beurich HW, Moosig F |title=[Atrial myxoma with clinical signs of systemic inflammatory disease.] |journal=Z Rheumatol |volume= |issue= |pages= |year=2014 |pmid=24599357 |doi=10.1007/s00393-013-1347-y |url=}}</ref> | ||
*[[Anemia]] - Normochromic or hypochromic | *[[Anemia]] - [[Normochromic anemia|Normochromic]] or [[Hypochromic anemia|hypochromic]] | ||
*[[Leukocytosis]] | *[[Leukocytosis]] | ||
*Elevated [[erythrocyte sedimentation rate]] (ESR) | *Elevated [[erythrocyte sedimentation rate]] (ESR) | ||
*Elevated [[C-reactive protein]] | *Elevated [[C-reactive protein]] | ||
*Serum globulin level (hypergammaglobulinemia): A1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of embolic accidents. <ref name="pmid10064362">{{cite journal |vauthors=Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I |title=Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience |journal=J Cardiovasc Surg (Torino) |volume=37 |issue=6 Suppl 1 |pages=113–7 |year=1996 |pmid=10064362 |doi= |url=}}</ref> | *Serum globulin level ([[hypergammaglobulinemia]]): A1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of [[embolic]] accidents. <ref name="pmid10064362">{{cite journal |vauthors=Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I |title=Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience |journal=J Cardiovasc Surg (Torino) |volume=37 |issue=6 Suppl 1 |pages=113–7 |year=1996 |pmid=10064362 |doi= |url=}}</ref> | ||
*Serum [[IL-6]]: Atrial myxoma cells are capable of producing IL-6. Consequently, IL-6 is used as a marker of recurrence in cardiac myxomas.<ref name="pmid26351445">{{cite journal |vauthors=Ezerioha N, Feng W |title=Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6 |journal=Case Rep Neurol |volume=7 |issue=2 |pages=152–5 |year=2015 |pmid=26351445 |pmc=4560324 |doi=10.1159/000437256 |url=}}</ref> | *Serum [[IL-6]]: Atrial myxoma cells are capable of producing [[Interleukin 6|Interleukin-6]] [[IL-6|(IL-6]]). Consequently, [[IL-6]] is used as a marker of recurrence in cardiac myxomas.<ref name="pmid26351445">{{cite journal |vauthors=Ezerioha N, Feng W |title=Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6 |journal=Case Rep Neurol |volume=7 |issue=2 |pages=152–5 |year=2015 |pmid=26351445 |pmc=4560324 |doi=10.1159/000437256 |url=}}</ref> | ||
==References== | ==References== |
Revision as of 15:05, 29 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]Maria Fernanda Villarreal, M.D. [3]
Overview
Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis, and elevated erythrocyte sedimentation rate. However, these results are generally non-diagnostic.[1]
Laboratory Findings
The clinical utility of laboratory tests in the diagnosis of cardiac myxoma remains nonspecific.[1] Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis and elevated erythrocyte sedimentation rate.
Blood tests
There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional symptoms are associated with the following cell blood count (CBC) findings:[2]
- Anemia - Normochromic or hypochromic
- Leukocytosis
- Elevated erythrocyte sedimentation rate (ESR)
- Elevated C-reactive protein
- Serum globulin level (hypergammaglobulinemia): A1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of embolic accidents. [3]
- Serum IL-6: Atrial myxoma cells are capable of producing Interleukin-6 (IL-6). Consequently, IL-6 is used as a marker of recurrence in cardiac myxomas.[4]
References
- ↑ 1.0 1.1 Reynen K (1995). "Cardiac myxomas". N. Engl. J. Med. 333 (24): 1610–7. doi:10.1056/NEJM199512143332407. PMID 7477198.
- ↑ Hartig I, Kraatz EG, Beurich HW, Moosig F (2014). "[Atrial myxoma with clinical signs of systemic inflammatory disease.]". Z Rheumatol. doi:10.1007/s00393-013-1347-y. PMID 24599357.
- ↑ Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I (1996). "Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience". J Cardiovasc Surg (Torino). 37 (6 Suppl 1): 113–7. PMID 10064362.
- ↑ Ezerioha N, Feng W (2015). "Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6". Case Rep Neurol. 7 (2): 152–5. doi:10.1159/000437256. PMC 4560324. PMID 26351445.