Amyloidosis physical examination: Difference between revisions
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==Physical Examination== | ==Physical Examination== | ||
Physical examination of patients withamyloidosis is usually remarkable for waxy thickening, easy bruising, purpura, macroglossia, [[parotid gland]] and submandibular gland enlargement, edema, numbness and paresthesia.<ref name="pmid267192344">{{cite journal |vauthors=Wechalekar AD, Gillmore JD, Hawkins PN |title=Systemic amyloidosis |journal=Lancet |volume=387 |issue=10038 |pages=2641–2654 |date=June 2016 |pmid=26719234 |doi=10.1016/S0140-6736(15)01274-X |url=}}</ref><ref name="pmid14660909">{{cite journal |vauthors=Pribitkin E, Friedman O, O'Hara B, Cunnane MF, Levi D, Rosen M, Keane WM, Sataloff RT |title=Amyloidosis of the upper aerodigestive tract |journal=Laryngoscope |volume=113 |issue=12 |pages=2095–101 |date=December 2003 |pmid=14660909 |doi=10.1097/00005537-200312000-00007 |url=}}</ref> | |||
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===Appearance of the Patient=== | ===Appearance of the Patient=== | ||
*Patients with amyloidosis usually appear normal. | *Patients with amyloidosis usually appear normal. | ||
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===Macular Amyloidosis=== | ===Macular Amyloidosis=== | ||
<gallery widths=130px> | <gallery widths="130px"> | ||
291.jpg | Macular Amyloidosis <br> [http://www.atlasdermatologico.com.br <font size="-2">''Adapted from Dermatology Atlas''</font>] | 291.jpg | Macular Amyloidosis <br> [http://www.atlasdermatologico.com.br <font size="-2">''Adapted from Dermatology Atlas''</font>] | ||
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===Nodular Amyloidosis=== | ===Nodular Amyloidosis=== | ||
<gallery widths=130px> | <gallery widths="130px"> | ||
297.jpg | Nodular Amyloidosis <br> [http://www.atlasdermatologico.com.br <font size="-2">''Adapted from Dermatology Atlas''</font>] | 297.jpg | Nodular Amyloidosis <br> [http://www.atlasdermatologico.com.br <font size="-2">''Adapted from Dermatology Atlas''</font>] | ||
Revision as of 16:09, 30 October 2019
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Risk calculators and risk factors for Amyloidosis physical examination |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2]
Overview
Common findings in amyloidosis include petechiae, ecchymosis, parotid gland enlargement, increased intraocular pressure, enlarged tongue, hepatomegaly, carpal tunnel syndrome, and Raynaud's phenomenon.
Physical Examination
Physical examination of patients withamyloidosis is usually remarkable for waxy thickening, easy bruising, purpura, macroglossia, parotid gland and submandibular gland enlargement, edema, numbness and paresthesia.[1][2]
Appearance of the Patient
- Patients with amyloidosis usually appear normal.
Vital signs
Skin
- Waxy thickening
- Easy bruising (ecchymoses)
- Subcutaneous nodules or plaques
- Purpura
- Petechiae
- Brittle nails
- Edema
- Diffuse or patchy alopecia
- Nail dystrophy
- Brittle nails
- Plaques may be seen
- Eyelids
- Retroauricular region
- Neck
- Inguinal and anogenital regions
HEENT
- Macroglossia
- Parotid gland enlargement
- Submandibular gland enlargement
- Peri-orbital purpura
- Raised intraocular pressure may be seen.
- Visual and hearing loss may be seen.
Neck
- Neck examination of patients with amyloidosis is usually normal.
Lungs
- Hoarseness
- Stridor
- Dysphagia
Heart
- Arrhythmia
Abdomen
Back
- Back examination of patients with amyloidosis is usually normal.
Genitourinary
- Genitourinary examination of patients with amyloidosis is usually normal.
Neuromuscular
- Numbness
- Paresthesia
- Pain
Extremities
- Edema
- Carpal tunnel syndrome
- Numbness of the fingers and toes
- Raynaud phenomenon
Macular Amyloidosis
-
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas -
Macular Amyloidosis
Adapted from Dermatology Atlas
Nodular Amyloidosis
-
Nodular Amyloidosis
Adapted from Dermatology Atlas -
Nodular Amyloidosis
Adapted from Dermatology Atlas -
Nodular Amyloidosis
Adapted from Dermatology Atlas -
Nodular Amyloidosis
Adapted from Dermatology Atlas
References
- ↑ Wechalekar AD, Gillmore JD, Hawkins PN (June 2016). "Systemic amyloidosis". Lancet. 387 (10038): 2641–2654. doi:10.1016/S0140-6736(15)01274-X. PMID 26719234.
- ↑ Pribitkin E, Friedman O, O'Hara B, Cunnane MF, Levi D, Rosen M, Keane WM, Sataloff RT (December 2003). "Amyloidosis of the upper aerodigestive tract". Laryngoscope. 113 (12): 2095–101. doi:10.1097/00005537-200312000-00007. PMID 14660909.