Familial amyloidosis CT scan: Difference between revisions
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==Overview== | ==Overview== | ||
[[Computed tomography|CT scan]] can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis. | |||
==CT scan== | ==CT scan== | ||
In hepatic amyloidosis, [[Computed tomography|CT scan]] findings may include: | |||
*[[Liver]] enlargement with [[heterogeneous]] decreased attenuation | |||
* Asymmetric and triangular [[hepatomegaly]] with the apex at the [[falciform ligament]] (due to mild [[Atrophy|atrophic]] change of the lateral border of both [[Liver|hepatic]] lobes) | |||
*[[Parenchyma|Parenchymal]] [[calcification]] (rare) | |||
In [[Kidney|renal]] amyloidosis, [[Computed tomography|CT scan]] findings may include: | |||
*[[Kidney]] enlargement with [[heterogeneous]] decreased attenuation | |||
*[[Parenchyma|Parenchymal]] [[calcification]] (rare) | |||
[ | |||
*[ | |||
*[ | |||
In [[Heart|cardiac]] amyloidosis, [[Computed tomography|CT scan]] findings may include<ref name="pmid24847009">{{cite journal| author=Falk RH, Quarta CC, Dorbala S| title=How to image cardiac amyloidosis. | journal=Circ Cardiovasc Imaging | year= 2014 | volume= 7 | issue= 3 | pages= 552-62 | pmid=24847009 | doi=10.1161/CIRCIMAGING.113.001396 | pmc=4118308 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24847009 }} </ref>: | |||
*[ | *[[Heart]] enlargement with [[heterogeneous]] decreased attenuation | ||
*[ | *[[Heart|Cardiac]] [[Calcification|calcifications]] | ||
*[ | *[[Pericardial effusion]] (rare) | ||
===Images=== | |||
[[File:Amyloidoma-mediastinal-1.jpg|300px|left|thumb| CT image showing mediastinal amyloidosis (yellow arrows). Case courtesy of Dr Natalie Yang, Radiopaedia.org, rID: 6711]] | |||
[[File:Amyloidosis-bronchial-and-diffuse-nodular-pulmonary-involvement.jpg|300px|center|thumb| Amyloidosis - bronchial and diffuse nodular pulmonary involvement. Case courtesy of Dr Bruno Di Muzio, Radiopaedia.org, rID: 60156]] | |||
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==References== | ==References== | ||
Revision as of 20:49, 4 November 2019
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Familial amyloidosis Microchapters |
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Familial amyloidosis CT scan On the Web |
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Risk calculators and risk factors for Familial amyloidosis CT scan |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
CT scan can be done to assess for amyloid deposition in particular organs. It can also be done to rule out other causes of organ dysfunction. However, MRI is more sensitive than CT in the diagnosis of amyloidosis.
CT scan
In hepatic amyloidosis, CT scan findings may include:
- Liver enlargement with heterogeneous decreased attenuation
- Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
- Parenchymal calcification (rare)
In renal amyloidosis, CT scan findings may include:
- Kidney enlargement with heterogeneous decreased attenuation
- Parenchymal calcification (rare)
In cardiac amyloidosis, CT scan findings may include[1]:
- Heart enlargement with heterogeneous decreased attenuation
- Cardiac calcifications
- Pericardial effusion (rare)
Images
References
- ↑ Falk RH, Quarta CC, Dorbala S (2014). "How to image cardiac amyloidosis". Circ Cardiovasc Imaging. 7 (3): 552–62. doi:10.1161/CIRCIMAGING.113.001396. PMC 4118308. PMID 24847009.