Lipoma overview: Difference between revisions
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==Overview== | ==Overview== | ||
A '''lipoma''' is a common, [[benign tumor]] composed of [[adipose tissue|fatty tissue]] | A '''lipoma''' is a common, [[benign tumor]] composed of [[adipose tissue|fatty tissue]]. | ||
==Historical Perspective== | ==Historical Perspective== | ||
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==Classification== | ==Classification== | ||
Lipoma may be [[Classification|classified]] into different subtypes depending on the [[classification]] system. They may be classified according to the [[anatomical]] location, the related [[tissues]] or other characteristics. | Lipoma may be [[Classification|classified]] into different subtypes depending on the [[classification]] system. They may be classified according to the [[anatomical]] location, the related [[tissues]] or other characteristics. | ||
==Pathophysiology== | ==Pathophysiology== | ||
Lipoma is formed from mature adipocyte cells and is histologically indistinguishable from [[fat tissue]]. Recent studies have observed [[Cytogenetics|cytogenetic]] abnormalities in 50-60% of lipomas, suggesting its role in the lipoma [[pathogenesis]]. Rearrangements of [[chromosome 12]] are the most commonly [[Cytogenetics|cytogenetic]] abnormality. In a [[cross-sectional]] appearance, the lipoma is pale yellow to orange and has a uniform greasy surface with a lobular pattern. The [[subcutaneous]] lipoma is usually encapsulated and has a distinct lobulated [[pattern]]. | |||
==Causes== | ==Causes== | ||
Revision as of 18:06, 21 November 2019
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Lipoma overview On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
A lipoma is a common, benign tumor composed of fatty tissue.
Historical Perspective
In 1914, Dr. Gery and colleagues first described Hibernoma, tumor of brown fat tissue.
Classification
Lipoma may be classified into different subtypes depending on the classification system. They may be classified according to the anatomical location, the related tissues or other characteristics.
Pathophysiology
Lipoma is formed from mature adipocyte cells and is histologically indistinguishable from fat tissue. Recent studies have observed cytogenetic abnormalities in 50-60% of lipomas, suggesting its role in the lipoma pathogenesis. Rearrangements of chromosome 12 are the most commonly cytogenetic abnormality. In a cross-sectional appearance, the lipoma is pale yellow to orange and has a uniform greasy surface with a lobular pattern. The subcutaneous lipoma is usually encapsulated and has a distinct lobulated pattern.