Lipoma overview: Difference between revisions
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==Natural History, Complications and Prognosis== | ==Natural History, Complications and Prognosis== | ||
Lipoma tends to affect individuals of 40 to 60 years of age. It affects [[trunk]], [[shoulder]], upper arm, and [[neck]] at a greater extent. They are completely [[benign]] and recurrence is one of their [[complications]]. | |||
==Diagnosis== | ==Diagnosis== | ||
Revision as of 16:09, 22 November 2019
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Lipoma overview On the Web |
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American Roentgen Ray Society Images of Lipoma overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
A lipoma is a common, benign tumor composed of fatty tissue.
Historical Perspective
In 1914, Dr. Gery and colleagues first described Hibernoma, tumor of brown fat tissue.
Classification
Lipoma may be classified into different subtypes depending on the classification system. They may be classified according to the anatomical location, the related tissues or other characteristics.
Pathophysiology
Lipoma is formed from mature adipocyte cells and is histologically indistinguishable from fat tissue. Recent studies have observed cytogenetic abnormalities in 50-60% of lipomas, suggesting its role in the lipoma pathogenesis. Rearrangements of chromosome 12 are the most commonly cytogenetic abnormality. In a cross-sectional appearance, the lipoma is pale yellow to orange and has a uniform greasy surface with a lobular pattern. The subcutaneous lipoma is usually encapsulated and has a distinct lobulated pattern.
Causes
There is no established cause for lipoma. However, trauma and some genetic abnormalities have been associated with its development.
Differentiating Lipoma other Diseases
Lipoma must be differentiated from liposarcoma, normal adipose tissue, adrenal myelolipoma, angiomyolipoma, and other lipomatous tumors.
Epidemiology and Demographics
Lipoma incidence is 100 per 100,000 individuals worldwide annually. Lipoma tend to affect middle age individuals, especially those of 40 to 60 years of age. It affects men at a greater extent than women.
Risk Factors
Common risk factors in the development of lipoma are trauma and genetic factors.
Screening
There is insufficent evidence to recommend routine screening for lipoma.
Natural History, Complications and Prognosis
Lipoma tends to affect individuals of 40 to 60 years of age. It affects trunk, shoulder, upper arm, and neck at a greater extent. They are completely benign and recurrence is one of their complications.