Myxoma laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with cardiac myxoma include [[anemia]], [[leukocytosis]], and elevated [[erythrocyte sedimentation rate]]. However, these results are generally non-diagnostic. | Laboratory findings consistent with cardiac myxoma include [[anemia]], [[leukocytosis]], and elevated [[erythrocyte sedimentation rate]]. However, these results are generally non-diagnostic. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
The clinical utility of laboratory tests in the diagnosis of cardiac myxoma remains nonspecific.<ref name="pmid7477198">{{cite journal |vauthors=Reynen K |title=Cardiac myxomas |journal=N. Engl. J. Med. |volume=333 |issue=24 |pages=1610–7 |year=1995 |pmid=7477198 |doi=10.1056/NEJM199512143332407 |url=}}</ref> Laboratory findings consistent with cardiac myxoma include [[anemia]], [[leukocytosis]] and elevated [[erythrocyte sedimentation rate]]. | The [[clinical]] utility of laboratory tests in the diagnosis of cardiac myxoma remains nonspecific.<ref name="pmid7477198">{{cite journal |vauthors=Reynen K |title=Cardiac myxomas |journal=N. Engl. J. Med. |volume=333 |issue=24 |pages=1610–7 |year=1995 |pmid=7477198 |doi=10.1056/NEJM199512143332407 |url=}}</ref> Laboratory findings consistent with cardiac myxoma include [[anemia]], [[leukocytosis]] and elevated [[erythrocyte sedimentation rate]]. | ||
===Blood tests=== | ===Blood tests=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]Maria Fernanda Villarreal, M.D. [3]
Overview
Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis, and elevated erythrocyte sedimentation rate. However, these results are generally non-diagnostic.
Laboratory Findings
The clinical utility of laboratory tests in the diagnosis of cardiac myxoma remains nonspecific.[1] Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis and elevated erythrocyte sedimentation rate.
Blood tests
There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional symptoms are associated with the following cell blood count (CBC) findings:[2]
- Anemia - Normochromic or hypochromic
- Leukocytosis
- Elevated erythrocyte sedimentation rate (ESR)
- Elevated C-reactive protein
- Serum globulin level (hypergammaglobulinemia): A1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of embolic accidents. [3]
- Serum IL-6: Atrial myxoma cells are capable of producing Interleukin-6 (IL-6). Consequently, IL-6 is used as a marker of recurrence in cardiac myxomas.[4]
References
- ↑ Reynen K (1995). "Cardiac myxomas". N. Engl. J. Med. 333 (24): 1610–7. doi:10.1056/NEJM199512143332407. PMID 7477198.
- ↑ Hartig I, Kraatz EG, Beurich HW, Moosig F (2014). "[Atrial myxoma with clinical signs of systemic inflammatory disease.]". Z Rheumatol. doi:10.1007/s00393-013-1347-y. PMID 24599357.
- ↑ Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I (1996). "Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience". J Cardiovasc Surg (Torino). 37 (6 Suppl 1): 113–7. PMID 10064362.
- ↑ Ezerioha N, Feng W (2015). "Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6". Case Rep Neurol. 7 (2): 152–5. doi:10.1159/000437256. PMC 4560324. PMID 26351445.