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__NOTOC__ 
{{CMG}}; {{AE}} {{NN}}


'''<font size="4">[[Acute Kidney Injury]]</font>'''
__NOTOC__
----
{{CMG}}; {{AE}} {{NN}}<br>
<br><br>
'''<font size="3">Overview</font>'''
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----


Acute kidney injury (AKI) or acute renal failure (ARF), is characterized by a rapid reduction of the renal filtration function, which is identified by a rise in serum creatinine concentration.<ref name="pmid15232604">{{cite journal| author=Schrier RW, Wang W, Poole B, Mitra A| title=Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. | journal=J Clin Invest | year= 2004 | volume= 114 | issue= 1 | pages= 5-14 | pmid=15232604 | doi=10.1172/JCI22353 | pmc=437979 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15232604  }} </ref> <br><br>'''<font size="3">Historical Perspective</font>'''
'''Acute Kidney Injury in COVID-19'''<br><br>
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'''For patient information, click [[Xyz (patient information)|here]]'''
'''<font size="3">Classification</font>'''
 
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*Acute kidney injury is classified into three main groups:<br>1. Prerenal<br>2. Renal<br>3. Postrenal<br>
 
{| border="1"
{{SK}} [[Acute Kidney Injury]], [[Acute Renal Failure]], [[AKI]], [[ARF]]
|+ '''lab findings in AKI'''
 
! Type !! UOsm !! UNa !! FeNa !! BUN/Cr
==[[Xyz overview|Overview]]==
|-
 
! Prerenal
==[[Xyz historical perspective|Historical Perspective]]==
| >500 || <10 || <1% || >20
 
|-
==[[Xyz classification|Classification]]==
! Renal
 
|<350 || >20  || >2%  ||<10-15
==[[Xyz pathophysiology|Pathophysiology]]==
|-
 
!Postrenal
==[[Xyz causes|Causes]]==
| <350 || >40 || >4% ||  >20
 
|}
==[[Xyz differential diagnosis|Differentiating Xyz from other Diseases]]==
<br />
 
{| class="wikitable"
==[[Xyz epidemiology and demographics|Epidemiology and Demographics]]==
|+
 
!Type
==[[Xyz risk factors|Risk Factors]]==
!UOsm
 
!UNa
==[[Xyz screening|Screening]]==
!FeNa
 
!BUN/Cr
==[[Xyz natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
|-
 
|Prerenal
==Diagnosis==
|>500
[[Xyz diagnostic study of choice|Diagnostic study of choice]] | [[Xyz history and symptoms|History and Symptoms]] | [[Xyz physical examination|Physical Examination]] | [[Xyz laboratory findings|Laboratory Findings]] | [[Xyz electrocardiogram|Electrocardiogram]] | [[Xyz x ray|X-Ray Findings]] | [[Xyz echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Xyz CT scan|CT-Scan Findings]] | [[Xyz MRI|MRI Findings]] | [[Xyz other imaging findings|Other Imaging Findings]] | [[Xyz other diagnostic studies|Other Diagnostic Studies]]
|<10
 
|<1%
==Treatment==
|>20
[[Xyz medical therapy|Medical Therapy]] | [[Xyz interventions|Interventions]] | [[Xyz surgery|Surgery]] | [[Xyz primary prevention|Primary Prevention]] | [[Xyz secondary prevention|Secondary Prevention]] | [[Xyz cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Xyz future or investigational therapies|Future or Investigational Therapies]]
|-
 
|Renal
==Case Studies==
|<350
[[Xyz case study one|Case #1]]
|>20
|>2%
|<10-15
|-
|Postrenal
|<350
|>40
|>4%
|>20
|}


*Acute kidney injury is classified into three main groups:
[[Category: (name of the system)]]
**[[Prerenal]]
**[[Renal]]
**[[Postrenal]]<br><br>
{{Family tree/start}}
{{familytree | | | | | | | | | B01 | | | | | |B01=<font color="blue">AKI</font>}}
{{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }}
{{familytree | | C01 | | | | | C02 | | | | | C03 |C01=[[Prerenal]]|C02=[[Renal]]|C03=[[Postrenal]]}}
{{Family tree| | | | | | | | | |!| | | | | | | | }}
{{familytree | | |,|-|-|-|-|-|-|+|-|-|-|-|-|-|.| }}
{{Family tree| | |D01 | | | | D02 | | | | D03| | D01=•[[Nephrotoxicity]]<br>• contrast dyes<br>• [[Rhabdomyolysis]]<br>|D02=• [[Ischemia]]<br>• [[Hypoxia]]<br>• Hypotension<br>|D03=• [[Inflammation]]<br>• [[Sepsis]]<br>• [[Infection]]<br>}}
{{Family tree/end}}<br><br><br>
[[File:Etiologies of AKI.jpg|800px|left]]

Revision as of 12:36, 15 June 2020