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Revision as of 18:14, 9 July 2020

Patients with chronic spontaneous urticaria are often frustrated and anxious
Although no external cause is identified in most patients, numerous factors can aggravate the condition.
Understanding these triggers and learning to avoid those that are relevant to the individual patient are critical components of successful management. Education should begin as soon as the diagnosis is made.
H1 antihistamines are recommended as initial therapy for all patients with chronic spontaneous Urticaria.
Less-sedating, second-generation agents (eg, cetirizine, levocetirizine, fexofenadine, loratadine, desloratadine)are more recommended over older first-generation agents (eg, hydroxyzine, diphenhydramine, chlorpheniramine, or mizolastine)

Around 50% of the patients may not achieve complete control of symptoms using standard doses of second-generation H1 antihistamines alone.
a stepwise approach to increasing therapy is appropriate for this patient group(Non Responders).
As we increase doses or as different agents are introduced, it is important to discontinue any that have not been beneficial, so that medications do not accumulate

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 * H1 antihistamines are recommended as initial therapy for all patients with chronic spontaneous Urticaria.
 *Less-sedating, second-generation agents (eg, cetirizine, levocetirizine, fexofenadine, loratadine, desloratadine)are more recommended over older first-generation agents (eg, hydroxyzine, diphenhydramine, chlorpheniramine, or mizolastine)
+===Treatment Response===
+*Around 50% of the patients may not achieve complete control of symptoms using standard doses of second-generation H1 antihistamines alone.
+*a stepwise approach to increasing therapy is appropriate for this patient group(Non Responders).
+*As we increase doses or as different agents are introduced, it is important to discontinue any that have not been beneficial, so that medications do not accumulate