Pheochromocytoma epidemiology and demographics: Difference between revisions
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* The [[prevalence]] of pheochromocytoma in individuals carrying a [[germline mutation]] in pheochromocytoma susceptibility [[genes]] may be around 50%. | * The [[prevalence]] of pheochromocytoma in individuals carrying a [[germline mutation]] in pheochromocytoma susceptibility [[genes]] may be around 50%. | ||
===Case-fatality rate/Mortality rate=== | |||
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%. | |||
*The case-fatality rate/mortality rate of [disease name] is approximately [number range]. | |||
=== Age === | === Age === | ||
* Patients of all age groups may develop pheochromocytoma. Approximately 10% occur in children. | * Patients of all age groups may develop pheochromocytoma. Approximately 10% occur in children. | ||
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===Gender=== | ===Gender=== | ||
* Pheochromocytoma affects men and women are equally. <ref name="cancergov" /> | * Pheochromocytoma affects men and women are equally. <ref name="cancergov" /> | ||
===Region=== | |||
*The majority of [disease name] cases are reported in [geographical region]. | |||
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2]. | |||
===Developed Countries=== | |||
===Developing Countries=== | |||
==References== | ==References== | ||
Revision as of 00:15, 25 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]Mohammed Abdelwahed M.D[3]
Overview
The incidence of pheochromocytoma ranges from a low of 0.2 per 100,000 persons to as high as 0.8 per 100,000 persons. The average age at diagnosis is 24.9 years in familial cases and 43.9 years in sporadic cases. Both men and women are affected equally by pheochromocytoma.
Epidemiology and Demographics
Incidence
- In the USA, the incidence of pheochromocytoma ranges from 0.2-0.8 per 100,000 persons.[1] [2]
- Annually reported cases range from 500 to 1600 in the United States.[3]
- Autopsy studies have discovered a higher number of cases than the actual prevalence rates. Ten percent of pheochromocytomas cases are discovered by chance.
Prevalence
- In the USA, the prevelance of pheochromocytoma ranges from 0.2-0.8 per 100,000 persons.[1]
- The prevalence of pheochromocytoma in patients with hypertension in general outpatient clinics ia about 0.1%. [4]
- The prevalence of pheochromocytoma is approximately 1.7% in children with hypertension.
- About 5% of patients with incidentally discovered adrenal masses on imaging actually have pheochromocytoma.
- The prevalence of pheochromocytoma in individuals carrying a germline mutation in pheochromocytoma susceptibility genes may be around 50%.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop pheochromocytoma. Approximately 10% occur in children.
- The median age at diagnosis is 40 years.
- The average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases.[1]
- Hereditary tumors present at a younger age than sporadic.
Race
- There is no racial predilection to pheochromocytoma.
Gender
- Pheochromocytoma affects men and women are equally. [1]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 1.2 1.3 National Cancer Institute. Physician Data Query Database 2015. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_25_toc
- ↑ Jameson, J (2017). Harrison's Principles of Internal Medicine 19th Edition and Harrison's Manual of Medicine 19th Edition VAL PAK. New York: McGraw-Hill Medical. ISBN 978-1260128857.
- ↑ Chen H, Sippel RS, O'Dorisio MS, Vinik AI, Lloyd RV, Pacak K; et al. (2010). "The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer". Pancreas. 39 (6): 775–83. doi:10.1097/MPA.0b013e3181ebb4f0. PMC 3419007. PMID 20664475.
- ↑ Jameson, J (2017). Harrison's Principles of Internal Medicine 19th Edition and Harrison's Manual of Medicine 19th Edition VAL PAK. New York: McGraw-Hill Medical. ISBN 978-1260128857.