Narcolepsy historical perspective: Difference between revisions

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===Discovery===
===Discovery===
*The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in patients, "with a sleepy disposition who suddenly falls fast asleep."
*The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in patients, "with a sleepy disposition who suddenly falls fast asleep."
*The first-ever convincing descriptions of narcolepsy and cataplexy were reported by Westphal (1877) and Fisher (1878) in Germany. They also observed a hereditary factor; the mother of Westphal's patient and a sister of Fisher's patient had similar features. They also reported the unique association of excitement and sleepiness triggering episodes of muscle weakness.
*The first-ever convincing descriptions of narcolepsy and cataplexy were reported by Westphal (1877) and Fisher (1878) in Germany.<ref name="Fischer1878">{{cite journal|last1=Fischer|first1=Franz|title=Epileptoide Schlafzustände|journal=Archiv für Psychiatrie und Nervenkrankheiten|volume=8|issue=1|year=1878|pages=200–203|issn=0003-9373|doi=10.1007/BF01791317}}</ref> They also observed a hereditary factor; the mother of Westphal's patient and a sister of Fisher's patient had similar features. They also reported the unique association of excitement and sleepiness triggering episodes of muscle weakness.
*French [[physician]] [[Jean-Baptiste-Édouard Gélineau]] (1880) described this [[condition]] in a wine merchant as [[neurosis]] or a functional [[condition]]. He gave narcolepsy its name, which is the English form of the French word '''narcolepsie''', and also recognized this [[disorder]] as a specific [[clinical]] entity.<ref name="pmid9132972">{{cite journal| author=Janković S, Susić V, Sokić D, Lević Z| title=[Dr. John Baptiste Edouard Gélineau]. | journal=Srp Arh Celok Lek | year= 1996 | volume= 124 | issue= 11-12 | pages= 331-5 | pmid=9132972 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9132972  }} </ref>
*French [[physician]] [[Jean-Baptiste-Édouard Gélineau]] (1880) described this [[condition]] in a wine merchant as [[neurosis]] or a functional [[condition]]. He gave narcolepsy its name, which is the English form of the French word '''narcolepsie''', and also recognized this [[disorder]] as a specific [[clinical]] entity.<ref name="pmid9132972">{{cite journal| author=Janković S, Susić V, Sokić D, Lević Z| title=[Dr. John Baptiste Edouard Gélineau]. | journal=Srp Arh Celok Lek | year= 1996 | volume= 124 | issue= 11-12 | pages= 331-5 | pmid=9132972 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9132972  }} </ref>



Revision as of 11:09, 1 August 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Muhammad Waleed Haider, M.D.[2]

Overview

Historical Perspective

Discovery

  • The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in patients, "with a sleepy disposition who suddenly falls fast asleep."
  • The first-ever convincing descriptions of narcolepsy and cataplexy were reported by Westphal (1877) and Fisher (1878) in Germany.[1] They also observed a hereditary factor; the mother of Westphal's patient and a sister of Fisher's patient had similar features. They also reported the unique association of excitement and sleepiness triggering episodes of muscle weakness.
  • French physician Jean-Baptiste-Édouard Gélineau (1880) described this condition in a wine merchant as neurosis or a functional condition. He gave narcolepsy its name, which is the English form of the French word narcolepsie, and also recognized this disorder as a specific clinical entity.[2]
  • The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
  • In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

Landmark Events in the Development of Treatment Strategies

Impact on Cultural History

Famous Cases

The following are a few famous cases of [disease name]:

References

  1. Fischer, Franz (1878). "Epileptoide Schlafzustände". Archiv für Psychiatrie und Nervenkrankheiten. 8 (1): 200–203. doi:10.1007/BF01791317. ISSN 0003-9373.
  2. Janković S, Susić V, Sokić D, Lević Z (1996). "[Dr. John Baptiste Edouard Gélineau]". Srp Arh Celok Lek. 124 (11–12): 331–5. PMID 9132972.

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