Narcolepsy historical perspective: Difference between revisions
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*The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in [[patients]], "with a sleepy [[Dispositional Affect|disposition]] who suddenly [[falls]] fast asleep." | *The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in [[patients]], "with a sleepy [[Dispositional Affect|disposition]] who suddenly [[falls]] fast asleep." | ||
*The first-ever convincing descriptions of narcolepsy and [[cataplexy]] were reported by Westphal (1877) and Fisher (1878) in Germany.<ref name="Fischer1878">{{cite journal|last1=Fischer|first1=Franz|title=Epileptoide Schlafzustände|journal=Archiv für Psychiatrie und Nervenkrankheiten|volume=8|issue=1|year=1878|pages=200–203|issn=0003-9373|doi=10.1007/BF01791317}}</ref> Both descriptions observed a [[hereditary]] factor in narcolepsy; the mother of Westphal's [[patient]] and a sister of Fisher's [[patient]] had similar [[clinical]] features. They also reported the unique [[Association (statistics)|association]] of excitement and [[sleepiness]] triggering episodes of [[muscle weakness]]. | *The first-ever convincing descriptions of narcolepsy and [[cataplexy]] were reported by Westphal (1877) and Fisher (1878) in Germany.<ref name="Fischer1878">{{cite journal|last1=Fischer|first1=Franz|title=Epileptoide Schlafzustände|journal=Archiv für Psychiatrie und Nervenkrankheiten|volume=8|issue=1|year=1878|pages=200–203|issn=0003-9373|doi=10.1007/BF01791317}}</ref> Both descriptions observed a [[hereditary]] factor in narcolepsy; the mother of Westphal's [[patient]] and a sister of Fisher's [[patient]] had similar [[clinical]] features. They also reported the unique [[Association (statistics)|association]] of excitement and [[sleepiness]] triggering episodes of [[muscle weakness]]. | ||
*French [[physician]] [[Jean-Baptiste-Édouard Gélineau]] (1880) described this [[condition]] in a wine merchant as [[neurosis]] or a functional [[condition]]. He gave narcolepsy its name, which is the English form of the French word '''narcolepsie''', and also recognized this [[disorder]] as a specific [[clinical]] entity.<ref name="pmid9132972">{{cite journal| author=Janković S, Susić V, Sokić D, Lević Z| title=[Dr. John Baptiste Edouard Gélineau]. | journal=Srp Arh Celok Lek | year= 1996 | volume= 124 | issue= 11-12 | pages= 331-5 | pmid=9132972 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9132972 }} </ref> | *French [[physician]] [[Jean-Baptiste-Édouard Gélineau]] (1880) described this [[condition]] in a wine merchant as [[neurosis]] or a functional [[condition]]. He gave narcolepsy its name, which is the English form of the French word '''narcolepsie''', and also recognized this [[disorder]] as a specific [[clinical]] entity.<ref name="pmid9132972">{{cite journal| author=Janković S, Susić V, Sokić D, Lević Z| title=[Dr. John Baptiste Edouard Gélineau]. | journal=Srp Arh Celok Lek | year= 1996 | volume= 124 | issue= 11-12 | pages= 331-5 | pmid=9132972 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9132972 }} </ref> Although Gélineau named this [[Distinctive feature|distinct]] [[clinical]] entity he did not [[differentiate]] episodes of [[muscle weakness]] and [[sleep]] attacks triggered by [[emotions]] as he proposed common [[physiology]] for these two [[Distinctive feature|distinct]] [[symptoms]] of narcolepsy. | ||
*The association between [important risk factor/cause] and [disease name] was made in/during [year/event]. | *The association between [important risk factor/cause] and [disease name] was made in/during [year/event]. | ||
Revision as of 11:30, 1 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Muhammad Waleed Haider, M.D.[2]
Overview
Historical Perspective
Discovery
- The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in patients, "with a sleepy disposition who suddenly falls fast asleep."
- The first-ever convincing descriptions of narcolepsy and cataplexy were reported by Westphal (1877) and Fisher (1878) in Germany.[1] Both descriptions observed a hereditary factor in narcolepsy; the mother of Westphal's patient and a sister of Fisher's patient had similar clinical features. They also reported the unique association of excitement and sleepiness triggering episodes of muscle weakness.
- French physician Jean-Baptiste-Édouard Gélineau (1880) described this condition in a wine merchant as neurosis or a functional condition. He gave narcolepsy its name, which is the English form of the French word narcolepsie, and also recognized this disorder as a specific clinical entity.[2] Although Gélineau named this distinct clinical entity he did not differentiate episodes of muscle weakness and sleep attacks triggered by emotions as he proposed common physiology for these two distinct symptoms of narcolepsy.
- The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
- In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
- In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
The following are a few famous cases of [disease name]:
References
- ↑ Fischer, Franz (1878). "Epileptoide Schlafzustände". Archiv für Psychiatrie und Nervenkrankheiten. 8 (1): 200–203. doi:10.1007/BF01791317. ISSN 0003-9373.
- ↑ Janković S, Susić V, Sokić D, Lević Z (1996). "[Dr. John Baptiste Edouard Gélineau]". Srp Arh Celok Lek. 124 (11–12): 331–5. PMID 9132972.