Renal agenesis history and symptoms: Difference between revisions
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== Symptoms == | == Symptoms == | ||
<br /> | Since patients with unilateral renal agenesis (URA) have an increased risk for [[proteinuria]], [[hypertension]], and [[renal insufficiency]], checking for symptoms of these complications should be considered.<ref name="pmid30734167" /> | ||
Checking for other contralateral [[Congenital disorder|congenital]] [[anomaly]] of [[kidney]] or [[Urinary system|urinary tract]] (CAKUT) such as [[Vesicoureteral reflux|VUR (vesicoureteral reflux)]] and PUJO (pelviureteric junction obstruction), extra-renal [[Anomaly|anomalies]] in different organs (such as [[Heart|cardiac]], [[lung]], [[Gastrointestinal tract|gastrointestinal]], [[Sex organ|genital]], [[skeleton]], and [[Vertebra|vertebral]]) , and associated syndromes and sequences (such as [[VACTERL association|VACTERL]], [[CHARGE syndrome|CHARGE]] and [[Edwards syndrome|Trisomy 18]]) should be considered when URA is diagnosed.<br /> | |||
==References== | ==References== | ||
Revision as of 14:22, 1 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
History
Maternal history during pregnancy for the following may be important in unilateral renal disease (URA):[1]
- Uncontrolled diabetes
- Treatment for hypertension
The following may be important to check in the family history of patients with URA:[2]
- URA
- CAKUT (congenital anomalies of the kidney and urinary tract)
- End stage renal disease (ESRD)
- Consanguinity
Symptoms
Since patients with unilateral renal agenesis (URA) have an increased risk for proteinuria, hypertension, and renal insufficiency, checking for symptoms of these complications should be considered.[2]
Checking for other contralateral congenital anomaly of kidney or urinary tract (CAKUT) such as VUR (vesicoureteral reflux) and PUJO (pelviureteric junction obstruction), extra-renal anomalies in different organs (such as cardiac, lung, gastrointestinal, genital, skeleton, and vertebral) , and associated syndromes and sequences (such as VACTERL, CHARGE and Trisomy 18) should be considered when URA is diagnosed.
References
- ↑ Woolf AS, Hillman KA (2007). "Unilateral renal agenesis and the congenital solitary functioning kidney: developmental, genetic and clinical perspectives". BJU Int. 99 (1): 17–21. doi:10.1111/j.1464-410X.2006.06504.x. PMID 16956352.
- ↑ 2.0 2.1 Xu Q, Wu H, Zhou L, Xie J, Zhang W, Yu H; et al. (2019). "The clinical characteristics of Chinese patients with unilateral renal agenesis". Clin Exp Nephrol. 23 (6): 792–798. doi:10.1007/s10157-019-01704-x. PMID 30734167.