Narcolepsy historical perspective: Difference between revisions
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*[[Cataplexy]] from the ''Greek'' '''kataplexis''' ([[Fixation (visual)|fixation]] of the [[eyes]]), was first named by Loëwenfeld (1902) as he was the first to name brief episodes of [[muscle weakness]] triggered by [[emotions]]. | *[[Cataplexy]] from the ''Greek'' '''kataplexis''' ([[Fixation (visual)|fixation]] of the [[eyes]]), was first named by Loëwenfeld (1902) as he was the first to name brief episodes of [[muscle weakness]] triggered by [[emotions]]. | ||
*Kinnier Wilson (1928) first coined the term, "[[Sleep paralysis|sleep paralysis.]]" | |||
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name]. | *In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name]. | ||
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name]. | *In [year], [gene] mutations were first implicated in the pathogenesis of [disease name]. | ||
Revision as of 15:00, 1 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Muhammad Waleed Haider, M.D.[2]
Overview
Historical Perspective
Discovery
- The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in patients, "with a sleepy disposition who suddenly falls fast asleep."
- The term narcolepsy is derived by combining the Greek narke numbness, stupor and lepsis attack, to seize.
- The first-ever convincing descriptions of narcolepsy and cataplexy were reported by Westphal (1877) and Fisher (1878) in Germany.[1] Both descriptions observed a hereditary factor in narcolepsy; the mother of Westphal's patient and a sister of Fisher's patient had similar clinical features. They also reported the unique association of excitement and sleepiness triggering episodes of muscle weakness.
- French physician Jean-Baptiste-Édouard Gélineau (1880) described this condition in a wine merchant as neurosis or a functional condition.[2] He gave narcolepsy its name, which is the English form of the French word narcolepsie, and also recognized this disorder as a specific clinical entity.[3] Although Gélineau named this distinct clinical entity he did not differentiate episodes of muscle weakness and sleep attacks triggered by emotions as he proposed common physiology for these two distinct symptoms of narcolepsy.
- Cataplexy from the Greek kataplexis (fixation of the eyes), was first named by Loëwenfeld (1902) as he was the first to name brief episodes of muscle weakness triggered by emotions.
- Kinnier Wilson (1928) first coined the term, "sleep paralysis."
- In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
- In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
The following are a few famous cases of [disease name]:
References
- ↑ Fischer, Franz (1878). "Epileptoide Schlafzustände". Archiv für Psychiatrie und Nervenkrankheiten. 8 (1): 200–203. doi:10.1007/BF01791317. ISSN 0003-9373.
- ↑ Schenck CH, Bassetti CL, Arnulf I, Mignot E (2007). "English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary". J Clin Sleep Med. 3 (3): 301–11. PMC 2564780. PMID 17561602.
- ↑ Janković S, Susić V, Sokić D, Lević Z (1996). "[Dr. John Baptiste Edouard Gélineau]". Srp Arh Celok Lek. 124 (11–12): 331–5. PMID 9132972.