Tricuspid atresia natural history, complications and prognosis: Difference between revisions
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* Early clinical features in infants include[[ cyanosis]] of [[lips]] and [[tongue]], [[difficulty in breathing]], [[tiring easily during feeding]]. | * Early clinical features in infants include[[ cyanosis]] of [[lips]] and [[tongue]], [[difficulty in breathing]], [[tiring easily during feeding]]. | ||
* The severity of [[cyanosis]] in infants with[[ pulmonary stenosis]] is dependent on the amount of[[ pulmonary blood flow ]]passing through[[ patent ductus arteriosus]]. | * The severity of [[cyanosis]] in[[ infants]] with [[ pulmonary stenosis]] is dependent on the amount of[[ pulmonary blood flow ]]passing through[[ patent ductus arteriosus]]. | ||
* After physiologic[[ patent ductus arteriosus]] (PDA) | * After physiologic closure of [[ patent ductus arteriosus]] (PDA), the[[ cyanosis]] will be aggravated. | ||
* In patients with normal pulmonary blood flow, complications of[[ heart failure]] may occur. | * In patients with normal[[ pulmonary blood flow]], complications of[[ heart failure]] may occur. | ||
* Prognosis is generally poor without [[surgery ]]and 90% of patients will die before 10 years old. | * Prognosis is generally poor without [[surgery ]]and 90% of patients will die before 10 years old. | ||
* The 15-year survival of patients with [[Fontan procedure]] is approximately %92 according to Merry et al. | * The 15-year survival of patients with [[Fontan procedure]] is approximately %92 according to Merry et al. |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Keri Shafer, M.D. [2] Priyamvada Singh, MBBS [3] Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]
Natural History, Complications and Prognosis
- Early clinical features in infants includecyanosis of lips and tongue, difficulty in breathing, tiring easily during feeding.
- The severity of cyanosis ininfants with pulmonary stenosis is dependent on the amount ofpulmonary blood flow passing throughpatent ductus arteriosus.
- After physiologic closure of patent ductus arteriosus (PDA), thecyanosis will be aggravated.
- In patients with normalpulmonary blood flow, complications ofheart failure may occur.
- Prognosis is generally poor without surgery and 90% of patients will die before 10 years old.
- The 15-year survival of patients with Fontan procedure is approximately %92 according to Merry et al.
Natural History, Complications, and Prognosis
Natural History
Complications
- Irregular, fast heart rhythms (arrhythmias)
- Chronic diarrhea (from a disease called protein losing enteropathy)
- Heart failure
- Fluid in the abdomen (ascites) and in the lungs (pleural effusion)
- Blockage of the artificial shunt
- Strokes and other neurological complications
- Sudden death
Prognosis
- The prognosis is poor in untreated patients.[1]
References
- ↑ Rao PS (2000). "Tricuspid Atresia". Curr Treat Options Cardiovasc Med. 2 (6): 507–520. doi:10.1007/s11936-000-0046-6. PMID 11096554.