Tricuspid atresia natural history, complications and prognosis: Difference between revisions
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* In patients with normal [[ pulmonary blood flow]], complications of [[ heart failure]] may occur. | * In patients with normal [[ pulmonary blood flow]], complications of [[ heart failure]] may occur. | ||
* Prognosis is generally poor without [[surgery ]] and 90% of patients will die before 10 years old. | * Prognosis is generally poor without [[surgery ]] and 90% of patients will die before 10 years old. | ||
* The 15-year survival of patients with [[Fontan procedure]] is approximately %92 | * The 15-year survival of patients with [[Fontan procedure]] is approximately %92.<ref name="MeryDe León2019">{{cite journal|last1=Mery|first1=Carlos M.|last2=De León|first2=Luis E.|last3=Trujillo-Diaz|first3=Daniel|last4=Ocampo|first4=Elena C.|last5=Dickerson|first5=Heather A.|last6=Zhu|first6=Huirong|last7=Adachi|first7=Iki|last8=Heinle|first8=Jeffrey S.|last9=Fraser|first9=Charles D.|last10=Ermis|first10=Peter R.|title=Contemporary Outcomes of the Fontan Operation: A Large Single-Institution Cohort|journal=The Annals of Thoracic Surgery|volume=108|issue=5|year=2019|pages=1439–1446|issn=00034975|doi=10.1016/j.athoracsur.2019.05.039}}</ref> | ||
** Complications of [[Fontan procedure]] include:<ref name="FredenburgJohnson2011">{{cite journal|last1=Fredenburg|first1=Tyler B.|last2=Johnson|first2=Tiffanie R.|last3=Cohen|first3=Mervyn D.|title=The Fontan Procedure: Anatomy, Complications, and Manifestations of Failure|journal=RadioGraphics|volume=31|issue=2|year=2011|pages=453–463|issn=0271-5333|doi=10.1148/rg.312105027}}</ref> | ** Complications of [[Fontan procedure]] include:<ref name="FredenburgJohnson2011">{{cite journal|last1=Fredenburg|first1=Tyler B.|last2=Johnson|first2=Tiffanie R.|last3=Cohen|first3=Mervyn D.|title=The Fontan Procedure: Anatomy, Complications, and Manifestations of Failure|journal=RadioGraphics|volume=31|issue=2|year=2011|pages=453–463|issn=0271-5333|doi=10.1148/rg.312105027}}</ref> | ||
Revision as of 08:10, 28 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief:Sara Zand, M.D.[2] Keri Shafer, M.D. [3] Priyamvada Singh, MBBS [4] Assistant Editor-In-Chief: Kristin Feeney, B.S. [5]
Natural History, Complications and Prognosis
- Early clinical features in infants include cyanosis of lips and tongue, difficulty in breathing, tiring easily during feeding.
- The severity of cyanosis in infants with pulmonary stenosis is dependent on the amount of pulmonary blood flow passing throughpatent ductus arteriosus.
- After physiologic closure of patent ductus arteriosus (PDA), the cyanosis will be aggravated.
- In patients with normal pulmonary blood flow, complications of heart failure may occur.
- Prognosis is generally poor without surgery and 90% of patients will die before 10 years old.
- The 15-year survival of patients with Fontan procedure is approximately %92.[1]
- Complications of Fontan procedure include:[2]
- Exercise intolerance due to ventricular failure
- Pericardial effusion andpleural effusion, chylothorax and protein-losing enteropathy due to lymphatic dysfunction
- Pulmonary embolism, blood clot formation in shunt
- Liver failure and portal hypertension as a result of increased pressure in the shunt
- leakage of theanastomosis
- Pulmonary hypertension
- Right atrium dilation
- Arrhythmia
References
- ↑ Mery, Carlos M.; De León, Luis E.; Trujillo-Diaz, Daniel; Ocampo, Elena C.; Dickerson, Heather A.; Zhu, Huirong; Adachi, Iki; Heinle, Jeffrey S.; Fraser, Charles D.; Ermis, Peter R. (2019). "Contemporary Outcomes of the Fontan Operation: A Large Single-Institution Cohort". The Annals of Thoracic Surgery. 108 (5): 1439–1446. doi:10.1016/j.athoracsur.2019.05.039. ISSN 0003-4975.
- ↑ Fredenburg, Tyler B.; Johnson, Tiffanie R.; Cohen, Mervyn D. (2011). "The Fontan Procedure: Anatomy, Complications, and Manifestations of Failure". RadioGraphics. 31 (2): 453–463. doi:10.1148/rg.312105027. ISSN 0271-5333.