Traumatic brain injury laboratory findings: Difference between revisions
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{{Traumatic brain injury}} | {{Traumatic brain injury}} | ||
==Overview== | |||
An elevated concentration of CSF spectrin breakdown product (SBDP)120 and SBDP145, ubiquitin C-terminal hydrolase-L1 (UCH-L1), and glial fibrillary acidic protein (GFAP) is diagnostic of traumatic brain injury. | |||
==Laboratory Findings== | |||
An elevated concentration of the following in CSF is diagnostic of traumatic brain injury.<ref name="pmid21171922">{{cite journal| author=Mondello S, Muller U, Jeromin A, Streeter J, Hayes RL, Wang KK| title=Blood-based diagnostics of traumatic brain injuries. | journal=Expert Rev Mol Diagn | year= 2011 | volume= 11 | issue= 1 | pages= 65-78 | pmid=21171922 | doi=10.1586/erm.10.104 | pmc=3063529 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21171922 }} </ref> | |||
*Spectrin breakdown product (SBDP)120 and SBDP145 | |||
*Ubiquitin C-terminal hydrolase-L1 (UCH-L1) | |||
*Glial fibrillary acidic protein (GFAP) | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 18:15, 1 September 2020
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Overview
An elevated concentration of CSF spectrin breakdown product (SBDP)120 and SBDP145, ubiquitin C-terminal hydrolase-L1 (UCH-L1), and glial fibrillary acidic protein (GFAP) is diagnostic of traumatic brain injury.
Laboratory Findings
An elevated concentration of the following in CSF is diagnostic of traumatic brain injury.[1]
- Spectrin breakdown product (SBDP)120 and SBDP145
- Ubiquitin C-terminal hydrolase-L1 (UCH-L1)
- Glial fibrillary acidic protein (GFAP)
References
- ↑ Mondello S, Muller U, Jeromin A, Streeter J, Hayes RL, Wang KK (2011). "Blood-based diagnostics of traumatic brain injuries". Expert Rev Mol Diagn. 11 (1): 65–78. doi:10.1586/erm.10.104. PMC 3063529. PMID 21171922.