Hemosiderosis classification: Difference between revisions
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==Classification== | ==Classification== | ||
*[[IPH]] may be | Based on the duration of symptoms, IPH may be classified as either acute or chronic phase. | ||
:*Group 1 pulmonary hemosiderosis involves PH with circulating anti-GMB antibodies. | * In acute phase, patients presents with sudden onset of severe dyspnea and hemoptysis, which, if not treated immediately, could be fatal. | ||
*In chronic phase, some children may present with weight loss and failure to thrive or hypoxemic respiratory failure. | |||
[[IPH]] may be classified into three groups based on disease characteristic: | |||
:*Group 1 pulmonary hemosiderosis involves PH with circulating anti-GMB antibodies which affecting the capillary system. | |||
:*Group 2 pulmonary hemosiderosis involves PH with an immune complex disease such as systemic lupus erythematosus, SLE. | :*Group 2 pulmonary hemosiderosis involves PH with an immune complex disease such as systemic lupus erythematosus, SLE. | ||
:*Group 3 pulmonary hemosiderosis involves no demonstrable immune system involvement. | :*Group 3 pulmonary hemosiderosis involves no demonstrable immune system involvement. |
Revision as of 05:38, 28 September 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
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Classification
Based on the duration of symptoms, IPH may be classified as either acute or chronic phase.
- In acute phase, patients presents with sudden onset of severe dyspnea and hemoptysis, which, if not treated immediately, could be fatal.
- In chronic phase, some children may present with weight loss and failure to thrive or hypoxemic respiratory failure.
IPH may be classified into three groups based on disease characteristic:
- Group 1 pulmonary hemosiderosis involves PH with circulating anti-GMB antibodies which affecting the capillary system.
- Group 2 pulmonary hemosiderosis involves PH with an immune complex disease such as systemic lupus erythematosus, SLE.
- Group 3 pulmonary hemosiderosis involves no demonstrable immune system involvement.