WBR0855

Author	[[PageAuthor::Mohamed Moubarak, M.D. [1]]]
Exam Type	ExamType::USMLE Step 3
Main Category
Sub Category	SubCategory::Infectious Disease
Prompt	[[Prompt::A 26 year- old male comes to your office in January complaining of dry cough, headache, sore throat, and feeling of tiredness started yesterday. He mentions a pain all over his body. On examination, the patient is feverish with temperature 39 C (102 F), heart rate 100/min, blood pressure 140/80 mmHg, and respiratory rate of 22/min. What is the best treatment of choice in managing this patient?]]
Answer A	AnswerA::Zanamivir
Answer A Explanation	[[AnswerAExp::Correct Neuraminidase inhibitor drugs (zanamivir and oseltamivir) are approved for both influenza A and influenza B, and the recommended to be used with Influenza]]
Answer B	AnswerB::Amantadine
Answer B Explanation	[[AnswerBExp::Incorrect The adamantane drugs (amantadine and rimantadine) are approved for influenza A only, and shouldn’t be used alone]]
Answer C	AnswerC::Rimantadine
Answer C Explanation	[[AnswerCExp::Incorrect The adamantane drugs (amantadine and rimantadine) are approved for influenza A only, and shouldn’t be used alone]]
Answer D	AnswerD::Tylenol and follow up
Answer D Explanation	[[AnswerDExp::Incorrect The patient is presented in the first 48 hours after the onset of symptoms, and antiviral therapy is recommended to be used]]
Answer E	AnswerE::Reassurance as it is a self limited disease
Answer E Explanation	[[AnswerEExp::Incorrect The patient is presented in the first 48 hours after the onset of influenza symptoms, and antiviral therapy is recommended to be used]]
Right Answer	RightAnswer::A
Explanation	[[Explanation::The adamantane drugs (amantadine and rimantadine) are approved for influenza A only, while the neuraminidase inhibitor drugs (zanamivir and oseltamivir) are approved for both influenza A and influenza B, and the recommended to be used when Influenza is the diagnosis if the patient presents within the first 48 hours after the onset of symptoms. In the United States, FDA-approved drugs against influenza are: amantadine, rimantadine, zanamivir (Relenza®), and oseltamivir (Tamiflu®). Educational Objective: References: ]]
Approved	Approved::No
Keyword	[[WBRKeyword::Influenza]]
Linked Question	Linked::
Order in Linked Questions	LinkedOrder::