Alopecia differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ogechukwu Hannah Nnabude, MD

Differentiating Alopecia from other Diseases

The following lists the complete differential diagnosis of Alopecia.

Non-Scarring Alopecia

• Adrenocortical insufficiency (primary or secondary)
• Anagen effluvium (anagen=growing hair)
• Cushing's syndrome
• Diffuse hair thinning due to metabolic causes
• Hyperthyroidism
• Hypoparathyroidism
• Hypothyroidism
• Pituitary insufficiency
• Secondary syphilis
• Sheehan's syndrome
• Telogen effluvium (telogen=resting hair)
• Temporary hair loss
  • Pregnancy
  • Malnutrition
    • Malabsorption
    • Protein deficiency
    • Tryptophan deficiency
    • Nontropical sprue
    • Vitamin A deficiency
    • Vitamin B deficiency
    • Vitamin D deficiency
    • Rickets
• Thyroiditis
• Trichotillomania

Scarring Alopecia

• Amyloidosis
• Chronic disciform lupus erythematosis
• Congenital defects
• Discoid Lupus Erythematosus
• Dissecting cellulitis
• Herpes zoster infection
• Infection
  • Favus
  • Typhoid Fever
  • Leptospirosis
  • Secondary syphilis
• Inflammatory dermatoses
• Lichen planopilaris
• Lymphoma
• Morphea
• Mycosis fungoides
• Neoplasm
• Neurodermatitis
• Physical or chemical agents:
  • ACE inhibitors
  • Allopurinol
  • Androgens
  • Anticoagulants
  • Anticonvulsants
  • Antimycotic agents
  • Arsenic
  • Azathioprine
  • Beta blockers
  • Borates
  • Cadmium
  • Chemotherapeutics
  • Chlorambucil
  • Cisplatin
  • Clofibrate
  • Cyclophosphamide
  • Cytarabine
  • Estrogens
  • Fluororacil
  • Gentamycin
  • Gold compounds
  • Heparins
  • Indomethacin
  • Levodopa
  • Linolic acid
  • Mercury and derivatives
  • Methotrexate
  • Niacin
  • Oral contraceptives
  • Propranolol
  • Retinoids
  • Salicylates
  • Selenium
  • Squalenes
  • Steroids
  • Thallium
  • Undecylenic acid
  • Vitamin A overdose
  • Warfarin
• Pseudofolliculitis barbae
• Psoriasis
• Sarcoidosis
• Scleroderma
• Systemic Lupus Erythematosus

Miscellaneous

• Addison's Disease
• Anemia
• Cancer
• Diabetes Mellitus
• Pneumonia
• Scarlet Fever
• Schmidt's Syndrome
• Stress
  • Labor
  • Surgery
• Testicular feminization syndrome
• Turner's Syndrome
• Typhoid fever
• Mechanical effects
  • Traction alopecia
  • Pressure alopecia (alopecia after extended bed rest)
  • Trichotillomania (compulsion to pull out one’s own hair)