Urticaria causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Urticaria}} | {{Urticaria}} | ||
{{CMG}}; {{AE}} {{Anahita}} | |||
==Overview== | ==Overview== | ||
Disease name] may be caused by [cause1], [cause2], or [cause3]. | |||
==Causes== | |||
===Life Thre | |||
atening Causes=== | |||
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. | Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. | ||
===Common Causes=== | ===Common Causes=== | ||
Common causes of [[urticaria]] may include: | |||
*[[Idiopathic]] | |||
**Unknown [[etiology]] | |||
*Immunological: | |||
#Autoimmune IgG autoantibodies to IgE Receptor or IgE on mast cells is the responsible mechanism. | |||
#IgE/contact: Contact with allergen cross-links specific IgE (SIgE) on mast cells. | |||
#Immune complex: | |||
##Mostly due to infections. | |||
##Urticarial vasculitis | |||
*Non-immunological: | |||
**Physical urticaria: Physical factors trigger histamine release from mast cells | |||
**Drug treatment: | |||
***Sensitivity to Cyclo-oxygenase (COX)-inhibitors | |||
***Direct mast cell histamine release | |||
**Dietary pseudo-allergens: Sensitivity to natural salicylates, colourings, preservatives. | |||
**Medical conditions: | |||
#Urticaria pigmentosa: Increased mast cell load | |||
#Cryopyrin-associated: Mutation in CIAS1 gene | |||
#Periodic syndrome (CAPS) | |||
==References== | ==References== |
Revision as of 17:43, 16 December 2020
Urticaria Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]
Overview
Disease name] may be caused by [cause1], [cause2], or [cause3].
Causes
===Life Thre
atening Causes=== Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
Common causes of urticaria may include:
- Idiopathic
- Unknown etiology
- Immunological:
- Autoimmune IgG autoantibodies to IgE Receptor or IgE on mast cells is the responsible mechanism.
- IgE/contact: Contact with allergen cross-links specific IgE (SIgE) on mast cells.
- Immune complex:
- Mostly due to infections.
- Urticarial vasculitis
- Non-immunological:
- Physical urticaria: Physical factors trigger histamine release from mast cells
- Drug treatment:
- Sensitivity to Cyclo-oxygenase (COX)-inhibitors
- Direct mast cell histamine release
- Dietary pseudo-allergens: Sensitivity to natural salicylates, colourings, preservatives.
- Medical conditions:
- Urticaria pigmentosa: Increased mast cell load
- Cryopyrin-associated: Mutation in CIAS1 gene
- Periodic syndrome (CAPS)