Urticaria causes: Difference between revisions

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{{Urticaria}}
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{{CMG}}; {{AE}} {{Anahita}}
==Overview==
==Overview==
Disease name] may be caused by [cause1], [cause2], or [cause3].
==Causes==
===Life Thre


==Causes==
atening Causes===
===Life Threatening Causes===
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.


===Common Causes===
===Common Causes===
Common causes of [[urticaria]] may include:
*[[Idiopathic]]
**Unknown [[etiology]]
*Immunological:
#Autoimmune IgG autoantibodies to IgE Receptor or IgE on mast cells is the responsible mechanism.
#IgE/contact: Contact with allergen cross-links specific IgE (SIgE) on mast cells.
#Immune complex:
##Mostly due to infections.
##Urticarial vasculitis
*Non-immunological:
**Physical urticaria: Physical factors trigger histamine release from mast cells
**Drug treatment:
***Sensitivity to Cyclo-oxygenase (COX)-inhibitors
***Direct mast cell histamine release
**Dietary pseudo-allergens: Sensitivity to natural salicylates, colourings, preservatives.
**Medical conditions:
#Urticaria pigmentosa: Increased mast cell load
#Cryopyrin-associated: Mutation in CIAS1 gene
#Periodic syndrome (CAPS)


==References==
==References==

Revision as of 17:43, 16 December 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]

Overview

Disease name] may be caused by [cause1], [cause2], or [cause3].

Causes

===Life Thre

atening Causes=== Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Common causes of urticaria may include:

  1. Autoimmune IgG autoantibodies to IgE Receptor or IgE on mast cells is the responsible mechanism.
  2. IgE/contact: Contact with allergen cross-links specific IgE (SIgE) on mast cells.
  3. Immune complex:
    1. Mostly due to infections.
    2. Urticarial vasculitis
  • Non-immunological:
    • Physical urticaria: Physical factors trigger histamine release from mast cells
    • Drug treatment:
      • Sensitivity to Cyclo-oxygenase (COX)-inhibitors
      • Direct mast cell histamine release
    • Dietary pseudo-allergens: Sensitivity to natural salicylates, colourings, preservatives.
    • Medical conditions:
  1. Urticaria pigmentosa: Increased mast cell load
  2. Cryopyrin-associated: Mutation in CIAS1 gene
  3. Periodic syndrome (CAPS)




References

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