Thin basement membrane disease history and symptoms: Difference between revisions
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{{Thin basement membrane disease}} | {{Thin basement membrane disease}} | ||
{{CMG}} | {{CMG}} | ||
{{AE}} {{MMT}} | |||
==Overview== | ==Overview== | ||
Obtaining complete [[History and Physical examination|history]] both for the patient and family is an important aspect of diagnosing [[TBMD]]. The hallmark of TBMD is [[Benign Recurrent Hamaturia|benign hematuria.]] A positive [[Family history|family histor]]<nowiki/>y of incidental finding of intermittent or [[Hematuria|persistent hematuria]] is suggestive of [[TBMD]]. TBMD is mostly asymptomatic. [[Microscopic hematuria]] is found incidentally. | Obtaining complete [[History and Physical examination|history]] both for the patient and family is an important aspect of diagnosing [[TBMD]]. The hallmark of TBMD is [[Benign Recurrent Hamaturia|benign hematuria.]] A positive [[Family history|family histor]]<nowiki/>y of incidental finding of intermittent or [[Hematuria|persistent hematuria]] is suggestive of [[TBMD]]. TBMD is mostly asymptomatic. [[Microscopic hematuria]] is found incidentally. |
Latest revision as of 09:37, 21 December 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]
Overview
Obtaining complete history both for the patient and family is an important aspect of diagnosing TBMD. The hallmark of TBMD is benign hematuria. A positive family history of incidental finding of intermittent or persistent hematuria is suggestive of TBMD. TBMD is mostly asymptomatic. Microscopic hematuria is found incidentally.
History and Symptoms
History
Obtaining complete medical and family history is an important aspect of diagnosing TBMD. It provides insight to cause and differentiation of TBMD with Alport syndrome, IgA nephropathy, Lupus Nephritis and other glomerulopathies. History may be obtained focusing specific areas including:
- Past medical history including URTI, Autoimmune Disease, Glomerulopathies.
- Positive family history of benign intermittent or persistent hematuria.
- Physical properties of urine (color, turbidity).
- Nature of micturation (frequency, dysuria)
- New onset hypertension or edema.
Symptoms
TBMD is mostly asymptomatic. The following signs are included:
- Intermiitent or persistent hematuria is found incidentally.
- New onset hypertension.
- Proteinuria.
- Renal impairment.
- Renal failure.