Lymphadenopathy classification: Difference between revisions
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Lymphadenopathy may be classified according to distribution into 2 groups localized lymphadenopathy and generalized lymphadenopathy. | Lymphadenopathy may be classified according to distribution into 2 groups localized lymphadenopathy and generalized lymphadenopathy. | ||
==Classification== | ==Classification== | ||
Depending upon the involvement of the lymph nodes, lymphadenopathy is classified into 2 groups:<ref name="pmid24753638">{{cite journal |vauthors=Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A |title=Peripheral lymphadenopathy: approach and diagnostic tools |journal=Iran J Med Sci |volume=39 |issue=2 Suppl |pages=158–70 |year=2014 |pmid=24753638 |pmc=3993046 |doi= |url=}}</ref> | Depending upon the involvement of the [[lymph nodes]], [[lymphadenopathy]] is classified into 2 groups:<ref name="pmid24753638">{{cite journal |vauthors=Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A |title=Peripheral lymphadenopathy: approach and diagnostic tools |journal=Iran J Med Sci |volume=39 |issue=2 Suppl |pages=158–70 |year=2014 |pmid=24753638 |pmc=3993046 |doi= |url=}}</ref> | ||
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*Localized lymphadenopathy: due to localized spot of [[infection]] e.g. an infected spot on the scalp will cause [[lymph nodes]] in the neck on that same side to swell up | *Localized lymphadenopathy: due to localized spot of [[infection]] e.g. an infected spot on the scalp will cause [[lymph nodes]] in the neck on that same side to swell up | ||
*[[Generalized lymphadenopathy]]: due to generalized infection all over the body e.g. [[influenza]] | *[[Generalized lymphadenopathy]]: due to generalized infection all over the body e.g. [[influenza]] | ||
**[[Persistent generalized lymphadenopathy]] (PGL): persisting for a long time, possibly without an apparent cause | **[[Persistent generalized lymphadenopathy]] (PGL): persisting for a long time, possibly without an apparent cause | ||
*Dermatopathic lymphadenopathy: lymphadenopathy associated with skin disease. [[Tangier disease]] (ABCA1 deficiency) may also cause this. | *Dermatopathic lymphadenopathy: [[lymphadenopathy]] associated with skin disease. [[Tangier disease]] (ABCA1 deficiency) may also cause this. | ||
[[Lymphadenopathy]] may be classified as follows: | [[Lymphadenopathy]] may be classified as follows: | ||
Revision as of 16:25, 16 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2], Raviteja Guddeti, M.B.B.S. [3]
Overview
Lymphadenopathy may be classified according to distribution into 2 groups localized lymphadenopathy and generalized lymphadenopathy.
Classification
Depending upon the involvement of the lymph nodes, lymphadenopathy is classified into 2 groups:[1]
- Localized lymphadenopathy: due to localized spot of infection e.g. an infected spot on the scalp will cause lymph nodes in the neck on that same side to swell up
- Generalized lymphadenopathy: due to generalized infection all over the body e.g. influenza
- Persistent generalized lymphadenopathy (PGL): persisting for a long time, possibly without an apparent cause
- Dermatopathic lymphadenopathy: lymphadenopathy associated with skin disease. Tangier disease (ABCA1 deficiency) may also cause this.
Lymphadenopathy may be classified as follows:
- By location:
- Dermatopathic lymphadenopathy: lymphadenopathy associated with skin disease.
- By malignancy: Benign lymphadenopathy is distinguished from malignant types which mainly refer to lymphomas or lymph node metastasis.
- By extent:
- Localized lymphadenopathy: due to localized spot of infection
- Generalized lymphadenopathy: due to systemic infection of the body. In some cases, it may persist for prolonged periods possibly without an apparent cause
- By size, where lymphadenopathy in adults is often defined as a short axis of one or more lymph nodes is greater than 10mm.[2][3]
References
- ↑ Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.
- ↑ Ganeshalingam S, Koh DM (December 2009). "Nodal staging". Cancer Imaging. 9: 104–11. doi:10.1102/1470-7330.2009.0017. PMC 2821588. PMID 20080453.
- ↑ Schmidt AF, Rodrigues OR, Matheus RS, Kim Jdu U, Jatene FB (2007). "Mediastinal lymph node distribution, size and number: definitions based on an anatomical study". J Bras Pneumol. 33 (2): 134–40. doi:10.1590/s1806-37132007000200006. PMID 17724531.