Menopause laboratory findings: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 5: | Line 5: | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of menopause include elevated [[Follicle Stimulating Hormone]] greater than 40 mIU/mL , and a decreased [[serum]] of the [https://rmanetwork.com/blog/anti-mullerian-hormone-amh-testing-of-ovarian-reserve/#:~:text=Maguire%3A%20AMH%2C%20or%20Anti%2D,a%20woman's%20overall%20egg%20count. Anti-Mullerian Hormone] level is a [[diagnostic test]] of [[premature menopause]]. | |||
| Line 13: | Line 13: | ||
<br /> | <br /> | ||
==laboratory findings== | ==laboratory findings== | ||
=== Natural menopause: === | |||
*An elevated [[serum]] of [[Follicle Stimulating Hormone]] ([[FSH]]) greater than 40 mIU/mL is diagnostic of [[menopause]].<ref name="pmid8124478">{{cite journal| author=Burger HG| title=Diagnostic role of follicle-stimulating hormone (FSH) measurements during the menopausal transition--an analysis of FSH, oestradiol and inhibin. | journal=Eur J Endocrinol | year= 1994 | volume= 130 | issue= 1 | pages= 38-42 | pmid=8124478 | doi=10.1530/eje.0.1300038 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8124478 }} </ref> | *An elevated [[serum]] of [[Follicle Stimulating Hormone]] ([[FSH]]) greater than 40 mIU/mL is diagnostic of [[menopause]].<ref name="pmid8124478">{{cite journal| author=Burger HG| title=Diagnostic role of follicle-stimulating hormone (FSH) measurements during the menopausal transition--an analysis of FSH, oestradiol and inhibin. | journal=Eur J Endocrinol | year= 1994 | volume= 130 | issue= 1 | pages= 38-42 | pmid=8124478 | doi=10.1530/eje.0.1300038 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8124478 }} </ref> | ||
*An elevated [[FSH]] level on two blood samples is diagnostic of [[premature menopause]] with intervals of about 4–6 weeks between samples | *An elevated [[FSH]] level on two blood samples is diagnostic of [[premature menopause]] with intervals of about 4–6 weeks between samples | ||
*A decreased [[serum]] of the | *A decreased [[serum]] of the [https://rmanetwork.com/blog/anti-mullerian-hormone-amh-testing-of-ovarian-reserve/#:~:text=Maguire%3A%20AMH%2C%20or%20Anti%2D,a%20woman's%20overall%20egg%20count. AMH] is normal in the [[Postmenopausal|postmenopause]] period.<ref name="pmid22231848">{{cite journal| author=Visser JA, Schipper I, Laven JS, Themmen AP| title=Anti-Müllerian hormone: an ovarian reserve marker in primary ovarian insufficiency. | journal=Nat Rev Endocrinol | year= 2012 | volume= 8 | issue= 6 | pages= 331-41 | pmid=22231848 | doi=10.1038/nrendo.2011.224 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22231848 }} </ref> | ||
*A decreased of [[Estrogen|estrogen Hormone l]]<nowiki/>evel in [[women]] with [[menopause]]. | *A decreased of [[Estrogen|estrogen Hormone l]]<nowiki/>evel in [[women]] with [[menopause]]. | ||
*[[karyotype]] analysis and testing for an ''[[FMR1]] for [[Fragile X syndrome]].'' | |||
*[[Thyroid-stimulating hormone]] ([[TSH]])<ref name="pmid29225794">{{cite journal| author=Torrealday S, Kodaman P, Pal L| title=Premature Ovarian Insufficiency - an update on recent advances in understanding and management. | journal=F1000Res | year= 2017 | volume= 6 | issue= | pages= 2069 | pmid=29225794 | doi=10.12688/f1000research.11948.1 | pmc=5710309 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29225794 }} </ref> | === Premature menopause: === | ||
* A decreased [[serum]] of the [https://rmanetwork.com/blog/anti-mullerian-hormone-amh-testing-of-ovarian-reserve/#:~:text=Maguire%3A%20AMH%2C%20or%20Anti%2D,a%20woman's%20overall%20egg%20count. Anti-Mullerian Hormone] level ([https://rmanetwork.com/blog/anti-mullerian-hormone-amh-testing-of-ovarian-reserve/#:~:text=Maguire%3A%20AMH%2C%20or%20Anti%2D,a%20woman's%20overall%20egg%20count. AMH]) is a [[diagnostic test]] of [[premature menopause]] | |||
* [[karyotype]] analysis and testing for an ''[[FMR1]] for [[Fragile X syndrome]].'' | |||
*Decrease of [[Thyroid-stimulating hormone]] ([[TSH]])<ref name="pmid29225794">{{cite journal| author=Torrealday S, Kodaman P, Pal L| title=Premature Ovarian Insufficiency - an update on recent advances in understanding and management. | journal=F1000Res | year= 2017 | volume= 6 | issue= | pages= 2069 | pmid=29225794 | doi=10.12688/f1000research.11948.1 | pmc=5710309 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29225794 }} </ref> | |||
Revision as of 19:24, 16 February 2021
|
Menopause Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Menopause laboratory findings On the Web |
|
American Roentgen Ray Society Images of Menopause laboratory findings |
|
Risk calculators and risk factors for Menopause laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Rahmah Al-Edresi, M.D.[2]
Overview
Laboratory findings consistent with the diagnosis of menopause include elevated Follicle Stimulating Hormone greater than 40 mIU/mL , and a decreased serum of the Anti-Mullerian Hormone level is a diagnostic test of premature menopause.
laboratory findings
Natural menopause:
- An elevated serum of Follicle Stimulating Hormone (FSH) greater than 40 mIU/mL is diagnostic of menopause.[1]
- An elevated FSH level on two blood samples is diagnostic of premature menopause with intervals of about 4–6 weeks between samples
- A decreased serum of the AMH is normal in the postmenopause period.[2]
- A decreased of estrogen Hormone level in women with menopause.
Premature menopause:
- A decreased serum of the Anti-Mullerian Hormone level (AMH) is a diagnostic test of premature menopause
- karyotype analysis and testing for an FMR1 for Fragile X syndrome.
- Decrease of Thyroid-stimulating hormone (TSH)[3]
References
- ↑ Burger HG (1994). "Diagnostic role of follicle-stimulating hormone (FSH) measurements during the menopausal transition--an analysis of FSH, oestradiol and inhibin". Eur J Endocrinol. 130 (1): 38–42. doi:10.1530/eje.0.1300038. PMID 8124478.
- ↑ Visser JA, Schipper I, Laven JS, Themmen AP (2012). "Anti-Müllerian hormone: an ovarian reserve marker in primary ovarian insufficiency". Nat Rev Endocrinol. 8 (6): 331–41. doi:10.1038/nrendo.2011.224. PMID 22231848.
- ↑ Torrealday S, Kodaman P, Pal L (2017). "Premature Ovarian Insufficiency - an update on recent advances in understanding and management". F1000Res. 6: 2069. doi:10.12688/f1000research.11948.1. PMC 5710309. PMID 29225794.