Metabolic alkalosis diagnostic study of choice: Difference between revisions

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=== Study of choice ===
=== Study of choice ===
* The following result of ABG is confirmatory of [disease name]:
* The following result of ABG is confirmatory of Metabolic Alkalosis:
** pH >7.45
** pH >7.45
** HCO3 >26 mEq/L
** HCO3 >26 mEq/L
Line 55: Line 55:
=== Diagnostic Criteria ===
=== Diagnostic Criteria ===
* The diagnosis of Metabolic Alkalosis is based on the [criteria name] criteria, which includes pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.
* The diagnosis of Metabolic Alkalosis is based on the [criteria name] criteria, which includes pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.


==References==
==References==

Revision as of 04:19, 21 February 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]

Overview

Arterial Blood Gas Analysis(ABG) is gold standard for diagnosis of Metabolic Alkalosis. Other laboratory tests, for instance Basic metabolic panel, serum aldosterone, serum renin, Urine analysis, urine pH, Urine chloride and sodium, Chest X-ray, Abdominal USG/CT are done to rule out the causes of metabolic alkalosis.

Diagnostic Study of Choice

Study of choice

  • The following result of ABG is confirmatory of Metabolic Alkalosis:
    • pH >7.45
    • HCO3 >26 mEq/L
    • PCO2 compensates for increased HCO3 by decreasing.
  • Investigations:
    • Among patients who present with clinical signs of Metabolic Alkalosis, the ABG is the most efficient test for diagnosis.

The comparison of various diagnostic studies for Metabolic alkalosis

Test Sensitivity Specificity
ABG <100% <100%
Central VBG 100% 100%

[1]

Diagnostic results

The following result of Arterial blood gas analysis is confirmatory of Metabolic Alkalosis:

    • pH >7.45
    • HCO3 >26 mEq/L
    • PCO2 compensates for increased HCO3 by decreasing.
Sequence of Diagnostic Studies

The various investigations must be performed in the following order:

    • ABG
    • Basic metabolic panel
    • Serum aldosterone
    • Serum renin
    • Urine analysis, Urine pH
    • Urine chloride and sodium
    • Chest X-ray
    • Abdominal USG/CT
    • Central VBG
    • Genetic Testing

Diagnostic Criteria

  • The diagnosis of Metabolic Alkalosis is based on the [criteria name] criteria, which includes pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.

References

  1. Schrauben SJ, Negoianu D, Costa C, Cohen RM, Goldfarb S, Fuchs BD, Berns JS (2018). "Accuracy of Acid-Base Diagnoses Using the Central Venous Blood Gas in the Medical Intensive Care Unit". Nephron. 139 (4): 293–298. doi:10.1159/000488501. PMC 6067967. PMID 29649820.

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