Metabolic alkalosis laboratory findings: Difference between revisions
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{{Metabolic alkalosis}} | {{Metabolic alkalosis}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{MMT}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of Metabolic Alkalosis include ABG (pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.), high or low Serum aldosterone/Serum renin, and Urine analysis with Urine pH and high or low Urine chloride and sodium. | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory findings consistent with the diagnosis of Metabolic Alkalosis | |||
**ABG (pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.) | |||
**Basic metabolic panel showing electrolytes imbalance. | |||
**Serum renin and aldosterone: | |||
High Renin, High aldosterone:• Malignant hypertension • renovascular hypertension • Renin secretin tumor | |||
Low Renin, High aldosterone:• Aldosterone secreting tumor • Adrenal hyperplasia • Glucocorticoid remediable aldosteronism | |||
Low Renin, Low Aldosterone:• Licorice • Liddle's syndrome • Enzyme deficiency | |||
**Urine analysis with Urine pH and Urine chloride and sodium: low urine Cl(• Gastric: Vomiting, NG suction • Lower bowel: Villous adenoma, chloridorrhea, laxative abuse), high urine Cl (• Non-reabsorbed ions: Penicillin • Impaired tubular transport: Loop and thiazide diuretics, Bartter's and Gitelman's disease, Hypomagnesaemia) | |||
*Some patients with Metabolic alkalosis may have severely reduced GFR with azotemia, which is usually suggestive of renal failure. | |||
*Some patients with | |||
==References== | ==References== |
Revision as of 04:46, 21 February 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]
Overview
Laboratory findings consistent with the diagnosis of Metabolic Alkalosis include ABG (pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.), high or low Serum aldosterone/Serum renin, and Urine analysis with Urine pH and high or low Urine chloride and sodium.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of Metabolic Alkalosis
- ABG (pH >7.45, HCO3 >26 mEq/L, PCO2 compensates for increased HCO3 by decreasing.)
- Basic metabolic panel showing electrolytes imbalance.
- Serum renin and aldosterone:
High Renin, High aldosterone:• Malignant hypertension • renovascular hypertension • Renin secretin tumor Low Renin, High aldosterone:• Aldosterone secreting tumor • Adrenal hyperplasia • Glucocorticoid remediable aldosteronism Low Renin, Low Aldosterone:• Licorice • Liddle's syndrome • Enzyme deficiency
- Urine analysis with Urine pH and Urine chloride and sodium: low urine Cl(• Gastric: Vomiting, NG suction • Lower bowel: Villous adenoma, chloridorrhea, laxative abuse), high urine Cl (• Non-reabsorbed ions: Penicillin • Impaired tubular transport: Loop and thiazide diuretics, Bartter's and Gitelman's disease, Hypomagnesaemia)
- Some patients with Metabolic alkalosis may have severely reduced GFR with azotemia, which is usually suggestive of renal failure.