Metabolic alkalosis natural history, complications and prognosis: Difference between revisions

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Latest revision as of 07:21, 21 February 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S [2]

Overview

Common complications of Metabolic alkalosis include hypokalemia, hypomagnesaemia, hypophosphatemia, coronary arterial blood flow reduction, arrhythmia, anaerobic glycolysis, reduced ventilation leading to low arterial oxygen saturation, increased CO2, decreased blood flow to cerebral arteries leading to altered mental status, lethargy, tetany, delirium, seizure.

Natural History, Complications, and Prognosis

Natural History

The mortality rate with metabolic alkalosis is 45% with arterial blood pH 7.55 to 80% with arterial blood pH of 7.65.

Complications

Common complications of Metabolic alkalosis include:
- Electrolyte imbalances: hypokalemia, hypomagnesaemia, hypophosphatemia
- Coronary arterial blood flow reduction leading to angina, refractory arrhythmia
- Anaerobic glycolysis
- Reduced ventilation leading to low arterial oxygen saturation, increased CO2
- Decreased blood flow to cerebral arteries leading to altered mental status, lethargy, tetany, delirium, seizure. .

Prognosis

Early stabilization of patient is associated with the most favorable prognosis.

References

Template:WH Template:WS

@@ Line 2: / Line 2: @@
 {{Metabolic alkalosis}}
-{{CMG}}; {{AE}}
+{{CMG}}; {{AE}} {{MMT}}
 ==Overview==
-If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
+Common complications of Metabolic alkalosis include hypokalemia, hypomagnesaemia, hypophosphatemia, coronary arterial blood flow reduction, arrhythmia, anaerobic glycolysis, reduced ventilation leading to low arterial oxygen saturation, increased CO2, decreased blood flow to cerebral arteries leading to altered mental status, lethargy, tetany, delirium, seizure.
-OR
-Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
-OR
-Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
 ==Natural History, Complications, and Prognosis==
 ===Natural History===
-*The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
-*The symptoms of (disease name) typically develop ___ years after exposure to ___.
+*The mortality rate with metabolic alkalosis is 45% with arterial blood pH 7.55 to 80% with arterial blood pH of 7.65.
-*If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
 ===Complications===
-*Common complications of [disease name] include:
+*Common complications of Metabolic alkalosis include:
-**[Complication 1]
+**Electrolyte imbalances: hypokalemia, hypomagnesaemia, hypophosphatemia
-**[Complication 2]
+**Coronary arterial blood flow reduction leading to angina, refractory arrhythmia
-**[Complication 3]
+**Anaerobic glycolysis
+**Reduced ventilation leading to low arterial oxygen saturation, increased CO2
+**Decreased blood flow to cerebral arteries leading to altered mental status, lethargy, tetany, delirium, seizure.   .
 ===Prognosis===
-*Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
+*Early stabilization of patient is associated with the most favorable prognosis.
-*Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
-*The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
-*[Subtype of disease/malignancy] is associated with the most favorable prognosis.
-*The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
 ==References==