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[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].


{| class="wikitable"
OR
!align="center" style="background: #4479BA; color: #FFFFFF | '''Common Cause of Tremor'''
 
! align="center" style="background: #4479BA; color: #FFFFFF| '''Differentiating Feature of Tremor'''  
[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
! align="center" style="background: #4479BA; color: #FFFFFF| '''Main Feature of Disease'''
 
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OR
| [[Essential tremor]] || Postural Tremor - [[Frequency]] 4–12 Hz, Bilateral onset || [[gait]] [[ataxia]], [[vestibulo-cerebellar]] involvement, reduced by [[alcohol]], [[family history]], [[stress]]/[[fatigue]] can increase tremor [[amplitude]], increases with voluntary movements
 
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As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
| [[Parkinson’s disease]] || [[Resting Tremor]] - Unilateral onset || [[Bradykinesia]], [[micrographia]], [[stooped posture]], [[ataxia]], [[rigidity]], [[imbalance]], [[depression]], [[apathy]], decreases with voluntary movements
 
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===Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]===
| [[Physiologic Tremor]] || Postural tremor - High [[frequency]] 8–10 Hz, low [[amplitude]], irregular oscillations || Tremor occurs while maintaining a posture and mostly disappears if [[eyes]] are closed or a load is placed on the [[muscles]]. Subtle [[innate]] tremor normally present in the general [[population]].
 
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On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].
| Enhanced [[Physiologic]] Tremor ||Increased [[amplitude]]  ||[[Physiologic]] tremor enhanced due to [[fatigue]], [[sleep deprivation]], [[drugs]], [[endocrine disorders]], [[caffeine]], [[stress]].
{|
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|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
| [[Cerebellar]] Tremor || [[Intention tremor]] - Low [[frequency]] <4 Hz || Occurs in [[multiple sclerosis]], [[stroke]], [[brainstem]] [[tumor]], or [[cerebellar]] [[trauma]]. May feature [[ataxia]], [[dysmetria]], [[dysdiadochokinesia]], and [[dysarthria]].
! rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
|-
| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Clinical manifestations'''
| [[Drug]] Induced Tremor || Can enhance rest, action, postural tremors || [[Amiodarone]], [[bronchodilators]], [[lithium]], [[metoclopramide]], [[neuroleptics]], [[theophylline]], [[valproate]]
! colspan="7" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Para-clinical findings
|-
| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Gold standard'''
| [[Orthostatic]] Tremor || [[Essential tremor]] variant, high [[frequency]] 14 Hz-18 Hz|| Occurs in the [[legs]] on standing and is relieved by sitting down
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|Additional findings
|-
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|Holmes tremor || Combination of rest, action, and postural tremors, [[Frequency]] 2Hz-5Hz || Mostly due to [[vascular]] [[lesion]] in [[mesencephalic]], [[thalamic]] or both regions.
| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Symptoms'''
! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical examination
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! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab Findings
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Histopathology
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! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 1
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 1
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 3
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 2
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 3
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!Diseases
!Symptom 1
! colspan="1" rowspan="1" |Symptom 2
!Symptom 3
!Physical exam 1
! colspan="1" rowspan="1" |Physical exam 2
!Physical exam 3
!Lab 1
!Lab 2
!Lab 3
!Imaging 1
!Imaging 2
!Imaging 3
!Histopathology
|'''Gold standard'''
!Additional findings
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 4
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 5
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 6
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Revision as of 15:33, 20 March 2021

[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].

OR

[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].

OR

As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].

Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]

On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Symptom 1 Symptom 2 Symptom 3 Physical exam 1 Physical exam 2 Physical exam 3 Lab 1 Lab 2 Lab 3 Imaging 1 Imaging 2 Imaging 3
Differential Diagnosis 1
Differential Diagnosis 2
Differential Diagnosis 3
Diseases Symptom 1 Symptom 2 Symptom 3 Physical exam 1 Physical exam 2 Physical exam 3 Lab 1 Lab 2 Lab 3 Imaging 1 Imaging 2 Imaging 3 Histopathology Gold standard Additional findings
Differential Diagnosis 4
Differential Diagnosis 5
Differential Diagnosis 6