Delirium future or investigational therapies: Difference between revisions
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===Prevention of [[Delirium]]=== | ===Prevention of [[Delirium]]=== | ||
*[[ Melatonin]]<ref name="GroverDua2019">{{cite journal|last1=Grover|first1=Sandeep|last2=Dua|first2=Devakshi|last3=Sahoo|first3=Swapnajeet|last4=Chakrabarti|first4=Subho|last5=Avasthi|first5=Ajit|title=Effectiveness of melatonin in the management of delirium: A retrospective study|journal=Journal of Mental Health and Human Behaviour|volume=24|issue=2|year=2019|pages=78|issn=0971-8990|doi=10.4103/jmhhb.jmhhb_56_19}}</ref> | *[[ Melatonin]]<ref name="GroverDua2019">{{cite journal|last1=Grover|first1=Sandeep|last2=Dua|first2=Devakshi|last3=Sahoo|first3=Swapnajeet|last4=Chakrabarti|first4=Subho|last5=Avasthi|first5=Ajit|title=Effectiveness of melatonin in the management of delirium: A retrospective study|journal=Journal of Mental Health and Human Behaviour|volume=24|issue=2|year=2019|pages=78|issn=0971-8990|doi=10.4103/jmhhb.jmhhb_56_19}}</ref> | ||
* [[Ramelteon]]<ref name="NishikimiNumaguchi2018">{{cite journal|last1=Nishikimi|first1=Mitsuaki|last2=Numaguchi|first2=Atsushi|last3=Takahashi|first3=Kunihiko|last4=Miyagawa|first4=Yasuhiro|last5=Matsui|first5=Kota|last6=Higashi|first6=Michiko|last7=Makishi|first7=Go|last8=Matsui|first8=Shigeyuki|last9=Matsuda|first9=Naoyuki|title=Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU|journal=Critical Care Medicine|volume=46|issue=7|year=2018|pages=1099–1105|issn=0090-3493|doi=10.1097/CCM.0000000000003132}}</ref> | * [[Ramelteon]]<ref name="NishikimiNumaguchi2018">{{cite journal|last1=Nishikimi|first1=Mitsuaki|last2=Numaguchi|first2=Atsushi|last3=Takahashi|first3=Kunihiko|last4=Miyagawa|first4=Yasuhiro|last5=Matsui|first5=Kota|last6=Higashi|first6=Michiko|last7=Makishi|first7=Go|last8=Matsui|first8=Shigeyuki|last9=Matsuda|first9=Naoyuki|title=Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU|journal=Critical Care Medicine|volume=46|issue=7|year=2018|pages=1099–1105|issn=0090-3493|doi=10.1097/CCM.0000000000003132}}</ref> | ||
* [[Dexmedetomidine]]<ref name="NgShubash2019">{{cite journal|last1=Ng|first1=K. T.|last2=Shubash|first2=C. J.|last3=Chong|first3=J. S.|title=The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis|journal=Anaesthesia|volume=74|issue=3|year=2019|pages=380–392|issn=00032409|doi=10.1111/anae.14472}}</ref> | * [[Dexmedetomidine]]<ref name="NgShubash2019">{{cite journal|last1=Ng|first1=K. T.|last2=Shubash|first2=C. J.|last3=Chong|first3=J. S.|title=The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis|journal=Anaesthesia|volume=74|issue=3|year=2019|pages=380–392|issn=00032409|doi=10.1111/anae.14472}}</ref> | ||
Revision as of 13:02, 21 April 2021
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Delirium Microchapters |
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Diagnosis |
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Treatment |
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Delirium On the Web |
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American Roentgen Ray Society Images of Delirium |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
Overview
There are many still unknown about delirium. Studies are being conducted to understand pathophysiology, more effective ways of prevention, utilization of EEG and CT/MRI scan etc.
Future or Investigational Therapies
Currently many studies are being conducted such as;
Prevention of Delirium
Studies to Improve Diagnosis and Prevention of Delirium
Studies to Understand Pathophysiology of Delirium
- Role of the immune system[7]
References
- ↑ Grover, Sandeep; Dua, Devakshi; Sahoo, Swapnajeet; Chakrabarti, Subho; Avasthi, Ajit (2019). "Effectiveness of melatonin in the management of delirium: A retrospective study". Journal of Mental Health and Human Behaviour. 24 (2): 78. doi:10.4103/jmhhb.jmhhb_56_19. ISSN 0971-8990.
- ↑ Nishikimi, Mitsuaki; Numaguchi, Atsushi; Takahashi, Kunihiko; Miyagawa, Yasuhiro; Matsui, Kota; Higashi, Michiko; Makishi, Go; Matsui, Shigeyuki; Matsuda, Naoyuki (2018). "Effect of Administration of Ramelteon, a Melatonin Receptor Agonist, on the Duration of Stay in the ICU". Critical Care Medicine. 46 (7): 1099–1105. doi:10.1097/CCM.0000000000003132. ISSN 0090-3493.
- ↑ Ng, K. T.; Shubash, C. J.; Chong, J. S. (2019). "The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis". Anaesthesia. 74 (3): 380–392. doi:10.1111/anae.14472. ISSN 0003-2409.
- ↑ Soh, Sarah; Shim, Jae-Kwang; Song, Jong-Wook; Choi, Nakcheoul; Kwak, Young-Lan (2019). "Preoperative transcranial Doppler and cerebral oximetry as predictors of delirium following valvular heart surgery: a case–control study". Journal of Clinical Monitoring and Computing. 34 (4): 715–723. doi:10.1007/s10877-019-00385-x. ISSN 1387-1307.
- ↑ Nitchingham, Anita; Kumar, Varun; Shenkin, Susan; Ferguson, Karen J.; Caplan, Gideon A. (2018). "A systematic review of neuroimaging in delirium: predictors, correlates and consequences". International Journal of Geriatric Psychiatry. 33 (11): 1458–1478. doi:10.1002/gps.4724. ISSN 0885-6230.
- ↑ Kimchi, Eyal Y.; Neelagiri, Anudeepthi; Whitt, Wade; Sagi, Avinash Rao; Ryan, Sophia L.; Gadbois, Greta; Groothuysen, Daniël; Westover, M. Brandon (2019). "Clinical EEG slowing correlates with delirium severity and predicts poor clinical outcomes". Neurology. 93 (13): e1260–e1271. doi:10.1212/WNL.0000000000008164. ISSN 0028-3878.
- ↑ Wang, Ping; Velagapudi, Ravikanth; Kong, Cuicui; Rodriguiz, Ramona M.; Wetsel, William C.; Yang, Ting; Berger, Miles; Gelbard, Harris A.; Colton, Carol A.; Terrando, Niccolò (2020). "Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia". Alzheimer's & Dementia. 16 (5): 734–749. doi:10.1002/alz.12064. ISSN 1552-5260.