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| ==References== | | ==References== |
| <ref name="pmid5044598">{{cite journal| author=Cotes JE, Field GB| title=Lung gas exchange in simple pneumoconiosis of coal workers. | journal=Br J Ind Med | year= 1972 | volume= 29 | issue= 3 | pages= 268-73 | pmid=5044598 | doi=10.1136/oem.29.3.268 | pmc=1009422 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=5044598 }} </ref>
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| {{Reflist|2}} | | {{Reflist|2}} |
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Revision as of 21:36, 30 April 2021
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dushka Riaz, MD
Overview
Pneumoconiosis must be differentiated from other diseases that cause chronic cough and dyspnea.
Differentiating Pneumoconiosis from other Diseases
Pneumoconiosis must be differentiated from other diseases that cause cough and dyspnea.
Differentiating pneumoconiosis from other diseases on the basis of dyspnea and cough
On the basis of cough and chronic dyspnea, pneumoconiosis must be differentiated from lung malignancy, tuberculosis, emphysema, asthma, interstitial lung disease, pneumonia, and sarcoidosis.
| Diseases
|
Clinical manifestations
|
Para-clinical findings
|
Gold standard
|
| Symptoms
|
Physical examination
|
| Lab Findings
|
Imaging
|
| Chronic Dyspnea
|
Cough
|
Fever
|
Spirometry
|
Auscultation
|
Night Sweats
|
CBC
|
ABG
|
Imaging
|
| Pneumoconiosis
|
+
|
+
|
+
|
↑ FEV1/FVC
|
Wheezing, rhonchi, crackles
|
+
|
↑WBC
|
↓O2, ↑CO2
|
Massive fibrosis, hilar adenopathy, reticular opacities, pleural plaques
|
HRCT
|
| Lung Malignancy
|
+
|
+
|
-
|
↓Vt, ↑RV
|
Wheezing, crackles
|
+
|
Normal
|
Normal
|
Mass lesion, hilar lymphadenopathy
|
Bronchoscopy
|
| Tuberculosis
|
+
|
+
|
+
|
Restrictive, obstructive, or mixed
|
Wheezing, rhonchi, crackles
|
+
|
↑WBC
|
↓O2, ↑CO2
|
Patchy consolidation, nodular opacities
|
IFN-y assay and acid fast stain
|
| Emphysema
|
+
|
+
|
-
|
↓ FEV1/FVC
|
Wheezing
|
-
|
Normal
|
Respiratory alkalosis, Metabolic acidosis
|
Flat diaphragm
|
Physical exam, spirometry
|
| Asthma
|
+
|
+
|
-
|
↓ FEV1/FVC
|
Wheezing
|
-
|
↑ Eosinophil
|
Respiratory alkalosis, Metabolic acidosis
|
Normal
|
Physical exam, spirometry before and after bronchodilator
|
| Interstitial lung diseases
|
+
|
+
|
-
|
↑ FEV1/FVC
|
Wheezing, rhonchi, crackles
|
+/-
|
Normal
|
↓O2, ↑CO2
|
Peripheral pulmonary infiltrative opacification
|
HRCT
|
| Sarcoidosis
|
+
|
+
|
-
|
↑ FEV1/FVC
|
Crackles
|
+
|
Normal
|
↓O2, ↑CO2
|
Hilar adenopathy
|
HRCT
|
| Pneumonia
|
+
|
+
|
+
|
Normal
|
Wheezing, rhonchi, crackles
|
+
|
↑WBC, neutrophilia
|
Normal
|
Lobar consolidation
|
CXR, CT Scan
|
References
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