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Effective measurement for primary prevention of [[atrioventricular block]] due to [[dogoxin toxicity]] in [[patients]] with [[renal insufficiency]] is avoidance of [[dehydration]], [[electrolytes imbalance]] and careful monitoring about [[heart block]]. | Effective measurement for primary prevention of [[atrioventricular block]] due to [[dogoxin toxicity]] in [[patients]] with [[renal insufficiency]] is avoidance of [[dehydration]], [[electrolytes imbalance]] and careful monitoring about [[heart block]]. | ||
==Primary prevention== | ==Primary prevention== | ||
*Effective measurement for primary prevention of [[atrioventricular block]] due to [[dogoxin toxicity]] in [[patients]] with [[renal insufficiency]] is avoidance of [[dehydration]], and [[electrolytes imbalance]]. | *Effective measurement for primary prevention of [[atrioventricular block]] due to [[dogoxin toxicity]] in [[patients]] with [[renal insufficiency]] is avoidance of [[dehydration]], and [[electrolytes imbalance]].<ref name="pmid6632915">{{cite journal |vauthors=Adamantidis MM, Duriez PR, Vincent AC, Dupuis BA |title=Digoxin-induced toxicity and experimental atrioventricular block in dogs. Relation between ventricular arrhythmias and oscillatory afterpotentials |journal=J Pharmacol |volume=14 |issue=3 |pages=333–49 |date=1983 |pmid=6632915 |doi= |url=}}</ref> | ||
* [[Patients]] with renal insufficiency, [[potassium]], [[electrolyte disturbances]], and [[dehydration]] are predisposed to develop [[digoxin toxicity]]. | * [[Patients]] with renal insufficiency, [[potassium]], [[electrolyte disturbances]], and [[dehydration]] are predisposed to develop [[digoxin toxicity]]. | ||
* Careful monitoring of electrolytes, drug levels, and [[renal function]] is essential in [[patients]] on [[chronic]] [[digoxin ]] therapy. | * Careful monitoring of electrolytes, drug levels, and [[renal function]] is essential in [[patients]] on [[chronic]] [[digoxin ]] therapy. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2]
Overview
Effective measurement for primary prevention of atrioventricular block due to dogoxin toxicity in patients with renal insufficiency is avoidance of dehydration, electrolytes imbalance and careful monitoring about heart block.
Primary prevention
- Effective measurement for primary prevention of atrioventricular block due to dogoxin toxicity in patients with renal insufficiency is avoidance of dehydration, and electrolytes imbalance.[1]
- Patients with renal insufficiency, potassium, electrolyte disturbances, and dehydration are predisposed to develop digoxin toxicity.
- Careful monitoring of electrolytes, drug levels, and renal function is essential in patients on chronic digoxin therapy.
- Patients on multiple AV nodal blocker agents (e.g., beta-blockers and calcium channel blockers) are at an increased risk for the development of atrioventricular (AV) block .
- These patients should be carefully monitored for heart blocks.