Diabetic foot laboratory findings: Difference between revisions
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*Presence of [[infection]] in [[diabetic foot|diabetic ulcers]] can worsen the [[Diabetes management|glycemic control]].<ref name="Lipsky2004">{{cite journal|last1=Lipsky|first1=Benjamin A.|title=A report from the international consensus on diagnosing and treating the infected diabetic foot|journal=Diabetes/Metabolism Research and Reviews|volume=20|issue=S1|year=2004|pages=S68–S77|issn=1520-7552|doi=10.1002/dmrr.453}}</ref> | *Presence of [[infection]] in [[diabetic foot|diabetic ulcers]] can worsen the [[Diabetes management|glycemic control]].<ref name="Lipsky2004">{{cite journal|last1=Lipsky|first1=Benjamin A.|title=A report from the international consensus on diagnosing and treating the infected diabetic foot|journal=Diabetes/Metabolism Research and Reviews|volume=20|issue=S1|year=2004|pages=S68–S77|issn=1520-7552|doi=10.1002/dmrr.453}}</ref> | ||
*For detection of main responsible [[microorganisms]] [[biopsy]], [[curettage]] or aspiration a tissue sample is recommended. It is recommended to obtain a sample from discharge of [[ulcer]]'s base. Moreover, due to contamination of all [[ulcers]] , culture from non-[[infection|infectious]] [[ulcers]] is not recommended.<ref name="pmid10480782">{{cite journal| author=American Diabetes Association| title=Consensus Development Conference on Diabetic Foot Wound Care: 7-8 April 1999, Boston, Massachusetts. American Diabetes Association. | journal=Diabetes Care | year= 1999 | volume= 22 | issue= 8 | pages= 1354-60 | pmid=10480782 | doi=10.2337/diacare.22.8.1354 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10480782 }} </ref> | *For detection of main responsible [[microorganisms]] [[biopsy]], [[curettage]] or aspiration a tissue sample is recommended. It is recommended to obtain a sample from discharge of [[ulcer]]'s base. Moreover, due to contamination of all [[ulcers]] , culture from non-[[infection|infectious]] [[ulcers]] is not recommended.<ref name="pmid10480782">{{cite journal| author=American Diabetes Association| title=Consensus Development Conference on Diabetic Foot Wound Care: 7-8 April 1999, Boston, Massachusetts. American Diabetes Association. | journal=Diabetes Care | year= 1999 | volume= 22 | issue= 8 | pages= 1354-60 | pmid=10480782 | doi=10.2337/diacare.22.8.1354 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10480782 }} </ref> | ||
*For confirming [[osteomyelitis]] [[diagnosis]] and for appropriate [[antibiotic]] [[treatment]], it is critical to obtain a [[bone]] [[biopsy]].<ref name="pmid9431370">{{cite journal| author=Lipsky BA| title=Osteomyelitis of the foot in diabetic patients. | journal=Clin Infect Dis | year= 1997 | volume= 25 | issue= 6 | pages= 1318-26 | pmid=9431370 | doi=10.1086/516148 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9431370 }} </ref> | |||
==References== | ==References== | ||
Revision as of 16:35, 6 July 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]
Overview
Laboratory Findings
- Even in deeply infected ulcers laboratory measures such as WBC, ESR and CRP might be normal. Nevertheless elevated measures demonstrate infection.[1]
- Presence of infection in diabetic ulcers can worsen the glycemic control.[2]
- For detection of main responsible microorganisms biopsy, curettage or aspiration a tissue sample is recommended. It is recommended to obtain a sample from discharge of ulcer's base. Moreover, due to contamination of all ulcers , culture from non-infectious ulcers is not recommended.[3]
- For confirming osteomyelitis diagnosis and for appropriate antibiotic treatment, it is critical to obtain a bone biopsy.[4]
References
- ↑ Lepäntalo, M.; Apelqvist, J.; Setacci, C.; Ricco, J.-B.; de Donato, G.; Becker, F.; Robert-Ebadi, H.; Cao, P.; Eckstein, H.H.; De Rango, P.; Diehm, N.; Schmidli, J.; Teraa, M.; Moll, F.L.; Dick, F.; Davies, A.H. (2011). "Chapter V: Diabetic Foot". European Journal of Vascular and Endovascular Surgery. 42: S60–S74. doi:10.1016/S1078-5884(11)60012-9. ISSN 1078-5884.
- ↑ Lipsky, Benjamin A. (2004). "A report from the international consensus on diagnosing and treating the infected diabetic foot". Diabetes/Metabolism Research and Reviews. 20 (S1): S68–S77. doi:10.1002/dmrr.453. ISSN 1520-7552.
- ↑ American Diabetes Association (1999). "Consensus Development Conference on Diabetic Foot Wound Care: 7-8 April 1999, Boston, Massachusetts. American Diabetes Association". Diabetes Care. 22 (8): 1354–60. doi:10.2337/diacare.22.8.1354. PMID 10480782.
- ↑ Lipsky BA (1997). "Osteomyelitis of the foot in diabetic patients". Clin Infect Dis. 25 (6): 1318–26. doi:10.1086/516148. PMID 9431370.