Alcoholic hepatitis other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Liver Biopsy=== | ===Liver Biopsy=== | ||
* [[liver biopsy]] is indicated in patients whose diagnosis is uncertain and in patients with severe | * [[liver biopsy]] is indicated in patients whose [[diagnosis]] is uncertain and in patients with [[severe]] [[Alcoholic Hepatitis]] who are probable to undergo medical treatment.<ref name="pmid20034030">{{cite journal| author=O'Shea RS, Dasarathy S, McCullough AJ, Practice Guideline Committee of the American Association for the Study of Liver Diseases. Practice Parameters Committee of the American College of Gastroenterology| title=Alcoholic liver disease. | journal=Hepatology | year= 2010 | volume= 51 | issue= 1 | pages= 307-28 | pmid=20034030 | doi=10.1002/hep.23258 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20034030 }} </ref> | ||
* Findings of liver biopsy in [[Alcoholic Hepatitis]] include:<ref name="pmid6110925">{{cite journal| author=| title=Alcoholic liver disease: morphological manifestations. Review by an international group. | journal=Lancet | year= 1981 | volume= 1 | issue= 8222 | pages= 707-11 | pmid=6110925 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6110925 }} </ref><ref name="pmid17222323">{{cite journal| author=Elphick DA, Dube AK, McFarlane E, Jones J, Gleeson D| title=Spectrum of liver histology in presumed decompensated alcoholic liver disease. | journal=Am J Gastroenterol | year= 2007 | volume= 102 | issue= 4 | pages= 780-8 | pmid=17222323 | doi=10.1111/j.1572-0241.2006.01034.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17222323 }} </ref> | * Findings of liver biopsy in [[Alcoholic Hepatitis]] include:<ref name="pmid6110925">{{cite journal| author=| title=Alcoholic liver disease: morphological manifestations. Review by an international group. | journal=Lancet | year= 1981 | volume= 1 | issue= 8222 | pages= 707-11 | pmid=6110925 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6110925 }} </ref><ref name="pmid17222323">{{cite journal| author=Elphick DA, Dube AK, McFarlane E, Jones J, Gleeson D| title=Spectrum of liver histology in presumed decompensated alcoholic liver disease. | journal=Am J Gastroenterol | year= 2007 | volume= 102 | issue= 4 | pages= 780-8 | pmid=17222323 | doi=10.1111/j.1572-0241.2006.01034.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17222323 }} </ref> | ||
** [[Polymorphonuclear cell|Polymorphonuclear]] infiltration | ** [[Polymorphonuclear cell|Polymorphonuclear]] infiltration | ||
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Other Diagnostic Studies
Liver Biopsy
- liver biopsy is indicated in patients whose diagnosis is uncertain and in patients with severe Alcoholic Hepatitis who are probable to undergo medical treatment.[1]
- Findings of liver biopsy in Alcoholic Hepatitis include:[2][3]
- Polymorphonuclear infiltration
- Hepatic necrosis
- Mallory bodies in hepatocytes
- Perivenular and perisinusoidal fibrosis
- Ballooning hepatocytes
- Steatosis
References
- ↑ O'Shea RS, Dasarathy S, McCullough AJ, Practice Guideline Committee of the American Association for the Study of Liver Diseases. Practice Parameters Committee of the American College of Gastroenterology (2010). "Alcoholic liver disease". Hepatology. 51 (1): 307–28. doi:10.1002/hep.23258. PMID 20034030.
- ↑ "Alcoholic liver disease: morphological manifestations. Review by an international group". Lancet. 1 (8222): 707–11. 1981. PMID 6110925.
- ↑ Elphick DA, Dube AK, McFarlane E, Jones J, Gleeson D (2007). "Spectrum of liver histology in presumed decompensated alcoholic liver disease". Am J Gastroenterol. 102 (4): 780–8. doi:10.1111/j.1572-0241.2006.01034.x. PMID 17222323.