Ancylostomiasis medical therapy: Difference between revisions
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*'''For stable uncomplicated cases''' | *'''For stable uncomplicated cases''' | ||
**'''Adult''' | **'''Adult''' | ||
***Preferred regimen: Albendazole 400 mg PO single dose | ***Preferred regimen: Albendazole 400 mg PO single dose.<ref name="pmid27929101">{{cite journal| author=Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R | display-authors=etal| title=Hookworm infection. | journal=Nat Rev Dis Primers | year= 2016 | volume= 2 | issue= | pages= 16088 | pmid=27929101 | doi=10.1038/nrdp.2016.88 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27929101 }} </ref> | ||
***Alternative regimen: Mebendazole 100 mg PO q12h for 3 days | ***Alternative regimen: Mebendazole 100 mg PO q12h for 3 days. | ||
***Alternative regimen: Pyrantel Pamoate 11mg/kg PO q24h for 3 days (maximum, 1gm per dose) | ***Alternative regimen: Pyrantel Pamoate 11mg/kg PO q24h for 3 days (maximum, 1gm per dose) | ||
**'''Pediatric''' | **'''Pediatric''' | ||
***'''children <2 years of age''' | ***'''children <2 years of age''' | ||
****Currently, for the [[treatment]] of young [[infants]], no guidelines are [[available]]. But current [[knowledge]] shows that the [[side effects]] linked to [[benzimidazole]] drugs in young children are likely to be the same as in older [[children]] and [[adults]]. Therefore, for the [[potential]] [[benefit]] of [[physical]] and [[cognitive development]], the [[treatment]] of [[young infants]] could be [[justified]].<ref name="pmid12745139">{{cite journal| author=Montresor A, Awasthi S, Crompton DW| title=Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasis. | journal=Acta Trop | year= 2003 | volume= 86 | issue= 2-3 | pages= 223-32 | pmid=12745139 | doi=10.1016/s0001-706x(03)00042-1 | pmc=5633076 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12745139 }} </ref> | ****Currently, for the [[treatment]] of young [[infants]], no guidelines are [[available]]. But current [[knowledge]] shows that the [[side effects]] linked to [[benzimidazole]] drugs in young children are likely to be the same as in older [[children]] and [[adults]]. Therefore, for the [[potential]] [[benefit]] of [[physical]] and [[cognitive development]], the [[treatment]] of [[young infants]] could be [[justified]].<ref name="pmid12745139">{{cite journal| author=Montresor A, Awasthi S, Crompton DW| title=Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasis. | journal=Acta Trop | year= 2003 | volume= 86 | issue= 2-3 | pages= 223-32 | pmid=12745139 | doi=10.1016/s0001-706x(03)00042-1 | pmc=5633076 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12745139 }} </ref> | ||
****Infant was treated with: | |||
*****Albendazole 200 mg PO single dose.<ref name="pmid20228435">{{cite journal| author=Bhatia V, Das MK, Kumar P, Arora NK| title=Infantile hookworm disease. | journal=Indian Pediatr | year= 2010 | volume= 47 | issue= 2 | pages= 190-2 | pmid=20228435 | doi=10.1007/s13312-010-0033-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20228435 }} </ref> | |||
*****Mebendazole 100 mg PO q12h for 3 days.<ref name="pmid33563313">{{cite journal| author=Umbrello G, Pinzani R, Bandera A, Formenti F, Zavarise G, Arghittu M | display-authors=etal| title=Hookworm infection in infants: a case report and review of literature. | journal=Ital J Pediatr | year= 2021 | volume= 47 | issue= 1 | pages= 26 | pmid=33563313 | doi=10.1186/s13052-021-00981-1 | pmc=7871578 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33563313 }} </ref> | |||
==References== | ==References== | ||
Revision as of 11:55, 19 August 2021
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Ancylostomiasis Microchapters |
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Ancylostomiasis medical therapy On the Web |
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Risk calculators and risk factors for Ancylostomiasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Anti-helminthic therapies are recommended among patients with ancylostomiasis. Efficacy of treatment varies according to the severity of infection, geographical distribution, and age groups.[1]
- For stable uncomplicated cases
- Adult
- Preferred regimen: Albendazole 400 mg PO single dose.[1]
- Alternative regimen: Mebendazole 100 mg PO q12h for 3 days.
- Alternative regimen: Pyrantel Pamoate 11mg/kg PO q24h for 3 days (maximum, 1gm per dose)
- Pediatric
- children <2 years of age
- Currently, for the treatment of young infants, no guidelines are available. But current knowledge shows that the side effects linked to benzimidazole drugs in young children are likely to be the same as in older children and adults. Therefore, for the potential benefit of physical and cognitive development, the treatment of young infants could be justified.[2]
- Infant was treated with:
- children <2 years of age
- Adult
References
- ↑ 1.0 1.1 Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R; et al. (2016). "Hookworm infection". Nat Rev Dis Primers. 2: 16088. doi:10.1038/nrdp.2016.88. PMID 27929101.
- ↑ Montresor A, Awasthi S, Crompton DW (2003). "Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasis". Acta Trop. 86 (2–3): 223–32. doi:10.1016/s0001-706x(03)00042-1. PMC 5633076. PMID 12745139.
- ↑ Bhatia V, Das MK, Kumar P, Arora NK (2010). "Infantile hookworm disease". Indian Pediatr. 47 (2): 190–2. doi:10.1007/s13312-010-0033-2. PMID 20228435.
- ↑ Umbrello G, Pinzani R, Bandera A, Formenti F, Zavarise G, Arghittu M; et al. (2021). "Hookworm infection in infants: a case report and review of literature". Ital J Pediatr. 47 (1): 26. doi:10.1186/s13052-021-00981-1. PMC 7871578 Check
|pmc=value (help). PMID 33563313 Check|pmid=value (help).