Bornholm disease pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
Group B | Group B [[Coxsackie virus|coxsackie]] viruses are transmitted from person to person by fecal-oral contamination, direct mouth-to-mouth contact or via droplet infection. Other people become infected with the [[virus]] if they touch contaminated items then put their fingers in their mouth before washing them properly. Contaminated items can include soiled diapers, shared toys and toilets. Epidemic pleurodynia is contagious and occurs in clusters, meaning many people in an area get it around the same time. | ||
The virus that causes [[devil's grip]] is [[picornavirus]]. It is spread by contact and epidemics usually occur during warm weather in temperate regions and at any time in the tropics. It can also be spread through [[saliva]] and feces<ref>http://www.medicomm.net/Consumer%20Site/dc/dc_b60.htm</ref>. Once inside the body via the [[pharynx]], the coxsackie viruses multiply in the throat and [[intestines]] as well as within the muscles of the [[Chest wall muscles|chest wall]], [[abdominal muscles]] and [[diaphragm]] after which it enters the [[lymphatic tissues]] <ref name="pmid30364740">{{cite journal| author=Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal| title=Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature. | journal=Respir Med Case Rep | year= 2018 | volume= 25 | issue= | pages= 270-273 | pmid=30364740 | doi=10.1016/j.rmcr.2018.10.005 | pmc=6197799 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30364740 }} </ref> and subsequently spreads into the bloodstream. At this point, the body's immune defences often can limit the infection and prevent the person from developing symptoms. If the immune defences are less successful, the person starts developing symptoms. | The virus that causes [[devil's grip]] is [[picornavirus]]. It is spread by contact and epidemics usually occur during warm weather in temperate regions and at any time in the tropics. It can also be spread through [[saliva]] and feces<ref>http://www.medicomm.net/Consumer%20Site/dc/dc_b60.htm</ref>. Once inside the body via the [[pharynx]], the coxsackie viruses multiply in the throat and [[intestines]] as well as within the muscles of the [[Chest wall muscles|chest wall]], [[abdominal muscles]] and [[diaphragm]] after which it enters the [[lymphatic tissues]] <ref name="pmid30364740">{{cite journal| author=Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M | display-authors=etal| title=Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature. | journal=Respir Med Case Rep | year= 2018 | volume= 25 | issue= | pages= 270-273 | pmid=30364740 | doi=10.1016/j.rmcr.2018.10.005 | pmc=6197799 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30364740 }} </ref> and subsequently spreads into the bloodstream. At this point, the body's immune defences often can limit the infection and prevent the person from developing symptoms. If the immune defences are less successful, the person starts developing symptoms. |
Revision as of 08:54, 15 February 2022
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz
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Overview
Bornholm disease is a disease caused by one of the group B coxsackie viruses and is less often caused by a group A coxsackie virus or an echovirus, causing pain in the muscles of the chest that join ribs together.
Pathophysiology
Group B coxsackie viruses are transmitted from person to person by fecal-oral contamination, direct mouth-to-mouth contact or via droplet infection. Other people become infected with the virus if they touch contaminated items then put their fingers in their mouth before washing them properly. Contaminated items can include soiled diapers, shared toys and toilets. Epidemic pleurodynia is contagious and occurs in clusters, meaning many people in an area get it around the same time.
The virus that causes devil's grip is picornavirus. It is spread by contact and epidemics usually occur during warm weather in temperate regions and at any time in the tropics. It can also be spread through saliva and feces[1]. Once inside the body via the pharynx, the coxsackie viruses multiply in the throat and intestines as well as within the muscles of the chest wall, abdominal muscles and diaphragm after which it enters the lymphatic tissues [2] and subsequently spreads into the bloodstream. At this point, the body's immune defences often can limit the infection and prevent the person from developing symptoms. If the immune defences are less successful, the person starts developing symptoms.
References
- ↑ http://www.medicomm.net/Consumer%20Site/dc/dc_b60.htm
- ↑ Lal A, Akhtar J, Isaac S, Mishra AK, Khan MS, Noreldin M; et al. (2018). "Unusual cause of chest pain, Bornholm disease, a forgotten entity; case report and review of literature". Respir Med Case Rep. 25: 270–273. doi:10.1016/j.rmcr.2018.10.005. PMC 6197799. PMID 30364740.