Gangrene overview: Difference between revisions

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==Overview==
==Overview==
Gangrene is a complication of [[necrosis]] (i.e., [[Cell (biology)|cell]] death) characterized by the decay of [[biological tissue|body tissue]]s, which become black and malodorous.  It is caused by [[infection]] or [[ischemia]], such as from [[thrombosis]] (blocked [[blood vessel]]). It is usually the result of critically insufficient [[blood]] supply (e.g., [[peripheral vascular disease]]) and is often associated with [[diabetes]] and long-term smoking. This condition is most common in the lower [[extremities]]. The best treatment for gangrene is [[revascularization]] (i.e., restoration of blood flow) of the affected organ, which can reverse some of the effects of necrosis and allow healing.  Other treatments include [[debridement]] and surgical [[amputation]].  The method of treatment is generally determined depending on location of affected tissue and extent of tissue loss. Gangrene may appear as one effect of foot binding.
 
==Historical Perspective==
==Historical Perspective==



Revision as of 05:44, 24 March 2022