Legionella pneumophila: Difference between revisions
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*''[[Legionella]]'' is non-fermentative and is unable to [[hydrolysis|hydrolyse]] [[gelatin]] or produce [[urease]]. | *''[[Legionella]]'' is non-fermentative and is unable to [[hydrolysis|hydrolyse]] [[gelatin]] or produce [[urease]]. | ||
*At least 46 species and 70 serogroups of ''[[Legionella]]'' have been identified. | *At least 46 species and 70 serogroups of ''[[Legionella]]'' have been identified. | ||
Legionella grow on buffered charcoal yeast enriched with L-cysteine <ref name="pmid16751507">{{cite journal| author=Ewann F, Hoffman PS| title=Cysteine metabolism in Legionella pneumophila: characterization of an L-cystine-utilizing mutant. | journal=Appl Environ Microbiol | year= 2006 | volume= 72 | issue= 6 | pages= 3993-4000 | pmid=16751507 | doi=10.1128/AEM.00684-06 | pmc=1489648 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16751507 }} </ref> | |||
*The natural habitat of Legionella is freshwater, where they often live within protozoa such as Vermamoeba vermiformis, Acanthamoeba spp., Tetrahymena pyriformis, and Naegleria spp <ref name="pmid11018138">{{cite journal| author=Swanson MS, Hammer BK| title=Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages. | journal=Annu Rev Microbiol | year= 2000 | volume= 54 | issue= | pages= 567-613 | pmid=11018138 | doi=10.1146/annurev.micro.54.1.567 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11018138 }} </ref>. It utilizes a similar method to enter and infect phagocytes. | |||
==Life Cycle== | ==Life Cycle== | ||
Revision as of 05:14, 20 April 2022
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Legionellosis Microchapters |
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Legionella pneumophila On the Web |
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American Roentgen Ray Society Images of Legionella pneumophila |
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Risk calculators and risk factors for Legionella pneumophila |
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| TEM image of L. pneumophila TEM image of L. pneumophila
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| Legionella pneumophila Brenner DJ, Steigerwalt AG, McDade JE 1979 |
This page is about microbiologic aspects of the organism(s). For clinical aspects of the disease, see Legionellosis.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
L.pneumophila is a ubiquitous aquatic organism that thrives in warm environments (32°- 45°C). L. pneumophila is a pleomorphic, aerobic, catalase-positive, oxidase-positive, non-spore-forming, non-capsulated, motile, Gram-negative bacteria. Although Legionella is categorized as a Gram-negative bacterium, it stains poorly to Gram stain due to its unique lipopolysaccharide-content in the outer psuedospamodulating leaflet of the outer cell membrane.
Microbiological Classification
Microbiological Characteristics
- L.pneumophila is a ubiquitous aquatic organism that thrives in warm environments (32°- 45°C).
- L. pneumophila is a pleomorphic, aerobic, catalase-positive, oxidase-positive, non-spore-forming, non-capsulated, motile, Gram-negative bacteria.
- Although Legionella is categorized as a Gram-negative bacterium, it stains poorly to Gram stain due to its unique lipopolysaccharide-content in the outer psuedospamodulating leaflet of the outer cell membrane.[1]
- Legionella is non-fermentative and is unable to hydrolyse gelatin or produce urease.
- At least 46 species and 70 serogroups of Legionella have been identified.
Legionella grow on buffered charcoal yeast enriched with L-cysteine [2]
- The natural habitat of Legionella is freshwater, where they often live within protozoa such as Vermamoeba vermiformis, Acanthamoeba spp., Tetrahymena pyriformis, and Naegleria spp [3]. It utilizes a similar method to enter and infect phagocytes.
Life Cycle
- There are two major phases to the life cycle.
- The first is called the replicative phase. During this period, the bacteria are nonmotile and have a low toxicity.
- In the second phase, called the infectious phase, the bacteria are shorter and thicker.
Gallery
References
- ↑ Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed. ed.). McGraw Hill. ISBN 0-8385-8529-9.
- ↑ Ewann F, Hoffman PS (2006). "Cysteine metabolism in Legionella pneumophila: characterization of an L-cystine-utilizing mutant". Appl Environ Microbiol. 72 (6): 3993–4000. doi:10.1128/AEM.00684-06. PMC 1489648. PMID 16751507.
- ↑ Swanson MS, Hammer BK (2000). "Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages". Annu Rev Microbiol. 54: 567–613. doi:10.1146/annurev.micro.54.1.567. PMID 11018138.
- ↑ Haney Carr, Janice. "Public Health Image Library". www.cdc.gov. Retrieved Jan 15 2016. Check date values in:
|access-date=(help) - ↑ Haney Carr, Janice. "Public Health Image Library". www.cdc.gov. Retrieved Jan 15 2016. Check date values in:
|access-date=(help) - ↑ Herbert, Anne. "Public Health Image Library". www.cdc.gov. Retrieved Jan 15 2016. Check date values in:
|access-date=(help)