Monkeypox causes: Difference between revisions
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==Causes== | ==Causes== | ||
* Monkeypox virus is a member of orthopoxvirus genus, which is a subdivision of Chordopoxvirinae that belongs to family Poxviridae<ref name="urlICTV">{{cite web |url=https://talk.ictvonline.org/taxonomy/ |title=ICTV |format= |work= |accessdate=}}</ref>. It is a linear double-stranded DNA virus that multiplies in the cytoplasm of infected cell<ref name="pmid9562888">{{cite journal| author=Holland J, Domingo E| title=Origin and evolution of viruses. | journal=Virus Genes | year= 1998 | volume= 16 | issue= 1 | pages= 13-21 | pmid=9562888 | doi=10.1023/a:1007989407305 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9562888 }} </ref>. | |||
* The virus has two genetic clades: the west African clade and the central African (Congo Basin) clade<ref name="pmid16186219">{{cite journal| author=Likos AM, Sammons SA, Olson VA, Frace AM, Li Y, Olsen-Rasmussen M | display-authors=etal| title=A tale of two clades: monkeypox viruses. | journal=J Gen Virol | year= 2005 | volume= 86 | issue= Pt 10 | pages= 2661-2672 | pmid=16186219 | doi=10.1099/vir.0.81215-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16186219 }} </ref>. | |||
Animal-to-animal, animal-to-human, and human-to-human are all possible routes to transmit the disease. Monkeypox can be transmitted by<ref name="urlCDC Monkeypox Response: Transmission | CDC Online Newsroom | CDC">{{cite web |url=https://www.cdc.gov/media/releases/2022/0509-monkeypox-transmission.html |title=CDC Monkeypox Response: Transmission | CDC Online Newsroom | CDC |format= |work= |accessdate=}}</ref> | |||
* Direct contact with body fluids or sores on the body of someone who has monkeypox | |||
* Direct contact with contaminated materials such as clothing or linens | |||
* Respiratory secretions when people have close, face-to-face contact | |||
Although most cases in 2022 were identified among men who have men with men, there is to date no evidence to support that monkeypox virus can be transmitted via vaginal fluids or semen<ref name="urlU.S. Monkeypox Outbreak 2022: Situation Summary | Monkeypox | Poxvirus | CDC">{{cite web |url=https://www.cdc.gov/poxvirus/monkeypox/response/2022/index.html |title=U.S. Monkeypox Outbreak 2022: Situation Summary | Monkeypox | Poxvirus | CDC |format= |work= |accessdate=}}</ref>. | |||
==References== | ==References== | ||
Revision as of 18:24, 14 June 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief:
Overview
Causes
- Monkeypox virus is a member of orthopoxvirus genus, which is a subdivision of Chordopoxvirinae that belongs to family Poxviridae[1]. It is a linear double-stranded DNA virus that multiplies in the cytoplasm of infected cell[2].
- The virus has two genetic clades: the west African clade and the central African (Congo Basin) clade[3].
Animal-to-animal, animal-to-human, and human-to-human are all possible routes to transmit the disease. Monkeypox can be transmitted by[4]
- Direct contact with body fluids or sores on the body of someone who has monkeypox
- Direct contact with contaminated materials such as clothing or linens
- Respiratory secretions when people have close, face-to-face contact
Although most cases in 2022 were identified among men who have men with men, there is to date no evidence to support that monkeypox virus can be transmitted via vaginal fluids or semen[5].
References
- ↑ "ICTV".
- ↑ Holland J, Domingo E (1998). "Origin and evolution of viruses". Virus Genes. 16 (1): 13–21. doi:10.1023/a:1007989407305. PMID 9562888.
- ↑ Likos AM, Sammons SA, Olson VA, Frace AM, Li Y, Olsen-Rasmussen M; et al. (2005). "A tale of two clades: monkeypox viruses". J Gen Virol. 86 (Pt 10): 2661–2672. doi:10.1099/vir.0.81215-0. PMID 16186219.
- ↑ "CDC Monkeypox Response: Transmission | CDC Online Newsroom | CDC".
- ↑ "U.S. Monkeypox Outbreak 2022: Situation Summary | Monkeypox | Poxvirus | CDC".