Monkeypox causes: Difference between revisions
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Monkeypox virus double-stranded DNA virus that belongs to family Poxviridae<ref name="urlICTV">{{cite web |url=https://talk.ictvonline.org/taxonomy/ |title=ICTV |format= |work= |accessdate=}}</ref><ref name="pmid9562888">{{cite journal| author=Holland J, Domingo E| title=Origin and evolution of viruses. | journal=Virus Genes | year= 1998 | volume= 16 | issue= 1 | pages= 13-21 | pmid=9562888 | doi=10.1023/a:1007989407305 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9562888 }} </ref>. It has two genetic clades: the west African clade and the central African (Congo Basin) clade<ref name="pmid16186219">{{cite journal| author=Likos AM, Sammons SA, Olson VA, Frace AM, Li Y, Olsen-Rasmussen M | display-authors=etal| title=A tale of two clades: monkeypox viruses. | journal=J Gen Virol | year= 2005 | volume= 86 | issue= Pt 10 | pages= 2661-2672 | pmid=16186219 | doi=10.1099/vir.0.81215-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16186219 }} </ref>. | Monkeypox virus double-stranded DNA virus that belongs to family Poxviridae<ref name="urlICTV">{{cite web |url=https://talk.ictvonline.org/taxonomy/ |title=ICTV |format= |work= |accessdate=}}</ref><ref name="pmid9562888">{{cite journal| author=Holland J, Domingo E| title=Origin and evolution of viruses. | journal=Virus Genes | year= 1998 | volume= 16 | issue= 1 | pages= 13-21 | pmid=9562888 | doi=10.1023/a:1007989407305 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9562888 }} </ref>. It has two genetic clades: the west African clade and the central African (Congo Basin) clade<ref name="pmid16186219">{{cite journal| author=Likos AM, Sammons SA, Olson VA, Frace AM, Li Y, Olsen-Rasmussen M | display-authors=etal| title=A tale of two clades: monkeypox viruses. | journal=J Gen Virol | year= 2005 | volume= 86 | issue= Pt 10 | pages= 2661-2672 | pmid=16186219 | doi=10.1099/vir.0.81215-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16186219 }} </ref>. | ||
Animal-to-human: virus can be acquired through daily exposure to an infected animal or complex exposure to an infected animal e.g. invasive bite or scratch that breaks the skin). Also through direct contact with lesions or bodily fluids of an infected animal. Human-to-human: The virus can be acquired through close physical contact with infected person, direct contact with lesions, bodily fluids, or respiratory secretions of an infected person, or direct contact with contaminated materials. <ref name="urlCDC Monkeypox Response: Transmission | CDC Online Newsroom | CDC">{{cite web |url=https://www.cdc.gov/media/releases/2022/0509-monkeypox-transmission.html |title=CDC Monkeypox Response: Transmission | CDC Online Newsroom | CDC |format= |work= |accessdate=}}</ref>. | |||
==Causes== | ==Causes== | ||
Revision as of 18:48, 14 June 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief:
Overview
Monkeypox virus double-stranded DNA virus that belongs to family Poxviridae[1][2]. It has two genetic clades: the west African clade and the central African (Congo Basin) clade[3].
Animal-to-human: virus can be acquired through daily exposure to an infected animal or complex exposure to an infected animal e.g. invasive bite or scratch that breaks the skin). Also through direct contact with lesions or bodily fluids of an infected animal. Human-to-human: The virus can be acquired through close physical contact with infected person, direct contact with lesions, bodily fluids, or respiratory secretions of an infected person, or direct contact with contaminated materials. [4].
Causes
Monkeypox virus is a member of orthopoxvirus genus, which is a subdivision of Chordopoxvirinae that belongs to family Poxviridae[1]. It is a linear double-stranded DNA virus that multiplies in the cytoplasm of infected cell[2]. The virus has two genetic clades: the west African clade and the central African (Congo Basin) clade[3].
Animal-to-human: The virus can be acquired through daily exposure to an infected animal or complex exposure to an infected animal e.g. invasive bite or scratch that breaks the skin). Also through direct contact with lesions or bodily fluids of an infected animal.
Human-to-human: The virus can be acquired through close physical contact with infected person, direct contact with lesions, bodily fluids, or respiratory secretions of an infected person, or direct contact with contaminated materials. [4]. The role of semen and vaginal fluids is being investigated[5].
References
- ↑ 1.0 1.1 "ICTV".
- ↑ 2.0 2.1 Holland J, Domingo E (1998). "Origin and evolution of viruses". Virus Genes. 16 (1): 13–21. doi:10.1023/a:1007989407305. PMID 9562888.
- ↑ 3.0 3.1 Likos AM, Sammons SA, Olson VA, Frace AM, Li Y, Olsen-Rasmussen M; et al. (2005). "A tale of two clades: monkeypox viruses". J Gen Virol. 86 (Pt 10): 2661–2672. doi:10.1099/vir.0.81215-0. PMID 16186219.
- ↑ 4.0 4.1 "CDC Monkeypox Response: Transmission | CDC Online Newsroom | CDC".
- ↑ "U.S. Monkeypox Outbreak 2022: Situation Summary | Monkeypox | Poxvirus | CDC".