Monkeypox history and symptoms: Difference between revisions
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|Criteria | |Criteria | ||
|- | |- | ||
|Suspected | | rowspan="2" |Suspected | ||
|New characteristic rash* OR | |New characteristic rash* '''OR''' | ||
|- | |- | ||
|Meets one of the epidemiologic criteria and has high clinical suspicion† for monkeypox | |Meets one of the epidemiologic criteria and has high clinical suspicion† for monkeypox | ||
|- | |- | ||
|Probable | | rowspan="4" |Probable | ||
|No suspicion of other recent orthopoxvirus exposure (e.g., Vaccinia virus in ACAM2000 vaccination) AND demonstration of the presence of | |No suspicion of other recent orthopoxvirus exposure (e.g., Vaccinia virus in ACAM2000 vaccination) '''AND''' demonstration of the presence of | ||
|- | |- | ||
|• Orthopoxvirus DNA by polymerase chain reaction testing of a clinical specimen '''OR''' | |||
|• Orthopoxvirus DNA by polymerase chain reaction testing of a clinical specimen OR | |||
|- | |- | ||
|• Orthopoxvirus using immunohistochemical or electron microscopy testing methods | |• Orthopoxvirus using immunohistochemical or electron microscopy testing methods | ||
'''OR''' | |||
OR | |||
|- | |- | ||
| | |• Detectable levels of antiorthopoxvirus IgM antibody during the period of 4–56 days after rash onset | ||
• Detectable levels of antiorthopoxvirus IgM antibody during the period of 4–56 days after rash onset | |||
|- | |- | ||
|Confirmed | | rowspan="2" |Confirmed | ||
|Demonstration of the presence of Monkeypox virus DNA by polymerase chain reaction testing or next-generation sequencing of a clinical specimen OR | |Demonstration of the presence of Monkeypox virus DNA by polymerase chain reaction testing or next-generation sequencing of a clinical specimen | ||
'''OR''' | |||
|- | |- | ||
|Isolation of Monkeypox virus in culture from a clinical specimen | |Isolation of Monkeypox virus in culture from a clinical specimen | ||
|} | |} | ||
__NOTOC__ | __NOTOC__ | ||
{{Monkeypox}} | {{Monkeypox}} | ||
Revision as of 20:33, 14 June 2022
Interim clinical, laboratory and epidemiologic criteria for case classification — U.S. Monkeypox Response, May 2022
| Clinical and laboratory classification | Criteria |
| Suspected | New characteristic rash* OR |
| Meets one of the epidemiologic criteria and has high clinical suspicion† for monkeypox | |
| Probable | No suspicion of other recent orthopoxvirus exposure (e.g., Vaccinia virus in ACAM2000 vaccination) AND demonstration of the presence of |
| • Orthopoxvirus DNA by polymerase chain reaction testing of a clinical specimen OR | |
| • Orthopoxvirus using immunohistochemical or electron microscopy testing methods
OR | |
| • Detectable levels of antiorthopoxvirus IgM antibody during the period of 4–56 days after rash onset | |
| Confirmed | Demonstration of the presence of Monkeypox virus DNA by polymerase chain reaction testing or next-generation sequencing of a clinical specimen
OR |
| Isolation of Monkeypox virus in culture from a clinical specimen |
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