Monkeypox history and symptoms: Difference between revisions
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Following the prodromal period, a rash develops with the following characteristics: | Following the prodromal period, a rash develops with the following characteristics: | ||
*Lesions develop and evolve at the same time | *Lesions develop and evolve at the same time | ||
*Lesions progresses from macular (1−2 days), papular (1−2 days), vesicular (1−2 days), to pustular (5-7 days), then scab (7-14 days) | *Lesions progresses from macular (1−2 days), papular (1−2 days), vesicular (1−2 days), to pustular (5-7 days), then scab (7-14 days)<ref name="urlClinical Recognition | Monkeypox | Poxvirus | CDC">{{cite web |url=https://www.cdc.gov/poxvirus/monkeypox/clinicians/clinical-recognition.html |title=Clinical Recognition | Monkeypox | Poxvirus | CDC |format= |work= |accessdate=2022-06-14}}</ref> | ||
===Diagnostic Criteria=== | ===Diagnostic Criteria=== | ||
Revision as of 21:38, 14 June 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Bassel Almarie, M.D.
Overview
History
The significant information in the patient's history include:
- Recent travel to endemic area
- Recent contact with person with similar complains or infected person with monkeypox
Symptoms
After infection, the incubation period lasts 7-14 days. Initial symptoms develop at the beginning of the prodromal period such as:
- Fever
- Chills
- Lymphadenopathy (distinctive feature of monkeypox)
- Headache
- Myalgia
Following the prodromal period, a rash develops with the following characteristics:
- Lesions develop and evolve at the same time
- Lesions progresses from macular (1−2 days), papular (1−2 days), vesicular (1−2 days), to pustular (5-7 days), then scab (7-14 days)[1]
Diagnostic Criteria
Clinical, laboratory and epidemiologic criteria for case classification — U.S. Monkeypox Response, May 2022
| Clinical and laboratory classification | Criteria |
| Suspected | New characteristic rash* OR |
| Meets one of the epidemiologic criteria and has high clinical suspicion† for monkeypox | |
| Probable | No suspicion of other recent orthopoxvirus exposure (e.g., Vaccinia virus in ACAM2000 vaccination) AND demonstration of the presence of |
| • Orthopoxvirus DNA by polymerase chain reaction testing of a clinical specimen OR | |
| • Orthopoxvirus using immunohistochemical or electron microscopy testing methods
OR | |
| • Detectable levels of antiorthopoxvirus IgM antibody during the period of 4–56 days after rash onset | |
| Confirmed | Demonstration of the presence of Monkeypox virus DNA by polymerase chain reaction testing or next-generation sequencing of a clinical specimen
OR |
| Isolation of Monkeypox virus in culture from a clinical specimen |
- ↑ "Clinical Recognition | Monkeypox | Poxvirus | CDC". Retrieved 2022-06-14.