Differentiating Anti-NMDA receptor encephalitis from other diseases: Difference between revisions
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| Limbic encephalitis, myoclonus | | Limbic encephalitis, myoclonus | ||
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| MRI T2/FLAIR hyperintensities, medial temporal | |||
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| 50% | |||
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| CSF pleocytosis or Oligoclonal Bands | |||
| 95% | |||
| 40% | |||
| 25% | |||
| 90% | |||
| 90% | |||
| some oligoclonal bands | |||
| 2/2 | |||
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Revision as of 11:19, 21 January 2023
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Anti-NMDA receptor encephalitis Microchapters |
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Differentiating Anti-NMDA receptor encephalitis from Other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Differentiating Anti-NMDA receptor encephalitis from other diseases On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ;AE Dheeraj Makkar, M.D.[2]
Overview
Differentiating Anti-NMDA Receptor Encephalitis from other Diseases
| Antigen | NMDA receptor NR1 | Lgil | CASPR2 | AMPA receptor | GABA B receptor | Glycine receptor | MgluR5
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|---|---|---|---|---|---|---|---|
| Age(median)/gender female : male | 0·6–85 (21) 4:1 | 30–80 (60) 1:2 | 46–77 (60) 1:4 | 38–87 (60) 9:1 | 24–75 (62) 1:1 | 5–69 (43) 6:5 | 46, 15 1:1 |
| Clinical syndrome | 1.Prodromal Syndrome
2. Psychiatric Syndrome, seizures, amnesia 3.Movement disorders catatonia, autonomic instability, |
Limbic encephalitis, tonic or facio-brachial dystonic seizures,
myoclonus
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Morvan Syndrome, encephalitis, neuromyotonia | Limbic encephalitis, psychiatric syndrome | Limbic encephalitis | Encephalomyelitis with rigidity and myoclonus, hyperekplexia, stiff-person syndrome,
(retinopathy) |
Limbic encephalitis, myoclonus |
| MRI T2/FLAIR hyperintensities, medial temporal | 25% | 80% | 40% | 90% | 70% | 10% | 50% |
| CSF pleocytosis or Oligoclonal Bands | 95% | 40% | 25% | 90% | 90% | some oligoclonal bands | 2/2 |