Sotorasib: Difference between revisions
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|offLabelPedNoGuideSupport=There is limited information regarding ''Off-Label Non–Guideline-Supported Use'' of Sotorasib in pediatric patients. | |offLabelPedNoGuideSupport=There is limited information regarding ''Off-Label Non–Guideline-Supported Use'' of Sotorasib in pediatric patients. | ||
|alcohol=Alcohol-Sotorasib interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. | |alcohol=Alcohol-Sotorasib interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. | ||
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Revision as of 17:37, 21 April 2025
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parth Vikram Singh, MBBS[2]
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Overview
Sotorasib is an inhibitor of the RAS GTPase that is FDA approved for the treatment of {{{indication}}}. Common adverse reactions include {{{adverseReactions}}}.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
There is limited information regarding Sotorasib FDA-Labeled Indications and Dosage (Adult) in the drug label.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Sotorasib in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Sotorasib in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Sotorasib FDA-Labeled Indications and Dosage (Pediatric) in the drug label.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Sotorasib in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Sotorasib in pediatric patients.
Contraindications
There is limited information regarding Sotorasib Contraindications in the drug label.
Warnings
There is limited information regarding Sotorasib Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Sotorasib Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Sotorasib Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Sotorasib Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Sotorasib in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Sotorasib in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Sotorasib during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Sotorasib in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Sotorasib in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Sotorasib in geriatric settings.
Gender
There is no FDA guidance on the use of Sotorasib with respect to specific gender populations.
Race
There is no FDA guidance on the use of Sotorasib with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Sotorasib in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Sotorasib in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Sotorasib in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Sotorasib in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Sotorasib Administration in the drug label.
Monitoring
There is limited information regarding Sotorasib Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Sotorasib and IV administrations.
Overdosage
There is limited information regarding Sotorasib overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
There is limited information regarding Sotorasib Pharmacology in the drug label.
Mechanism of Action
There is limited information regarding Sotorasib Mechanism of Action in the drug label.
Structure
There is limited information regarding Sotorasib Structure in the drug label.
Pharmacodynamics
There is limited information regarding Sotorasib Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Sotorasib Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Sotorasib Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Sotorasib Clinical Studies in the drug label.
How Supplied
There is limited information regarding Sotorasib How Supplied in the drug label.
Storage
There is limited information regarding Sotorasib Storage in the drug label.
Images
Drug Images
{{#ask: Page Name::Sotorasib |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}
Package and Label Display Panel
{{#ask: Label Page::Sotorasib |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}
Patient Counseling Information
There is limited information regarding Sotorasib Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Sotorasib interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
LUMAKRAS
Look-Alike Drug Names
There is limited information regarding Sotorasib Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.