Mixed gliomas: Difference between revisions
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== Overview == | == Overview == | ||
Oligoastrocytomas are a subset of [[brain tumor]] that present with an appearance of mixed glial cell origin, [[astrocytoma]] and [[oligodendroglioma]]. Often called a "mixed glioma", about 2.3% of all reported brain tumors are diagnosed as oligoastrocytoma. The median age of diagnosis is 42 years of age. | Oligoastrocytomas are a subset of [[brain tumor]] that present with an appearance of mixed glial cell origin, [[astrocytoma]] and [[oligodendroglioma]]. Often called a "mixed glioma", about 2.3% of all reported brain tumors are diagnosed as oligoastrocytoma. The median age of diagnosis is 42 years of age. | ||
Oligoastrocytomas, like [[astrocytomas]] and oligodendrogliomas, can have malignant ([[anaplastic]]) histology. However, lower grades can have less aggressive biology. | Oligoastrocytomas, like [[astrocytomas]] and oligodendrogliomas, can have malignant ([[anaplastic]]) histology. However, lower grades can have less aggressive biology. | ||
==Symptoms== | ==Symptoms== | ||
There are many possible symptoms of oligodendrogliomas that are similar to other [[glioma]]s. These symptoms may include [[headache]], [[seizure]] and speech or motor changes. | There are many possible symptoms of oligodendrogliomas that are similar to other [[glioma]]s. These symptoms may include [[headache]], [[seizure]] and speech or motor changes. | ||
==Diagnosis== | ==Diagnosis== | ||
A [[Computed Tomography]] (CT) or [[Magnetic Resonance Imaging]] (MRI) scan is necessary to characterize the anatomy of this tumor (size, location, heter/homogeneity). However, final diagnosis of this [[tumor]], like most tumors, relies on [[histopathologic]] examination ([[biopsy]] examination). | A [[Computed Tomography]] (CT) or [[Magnetic Resonance Imaging]] (MRI) scan is necessary to characterize the anatomy of this tumor (size, location, heter/homogeneity). However, final diagnosis of this [[tumor]], like most tumors, relies on [[histopathologic]] examination ([[biopsy]] examination). | ||
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==Prognosis== | ==Prognosis== | ||
Even after surgery, an oligoastrocytoma will often recur. The treatment for a recurring brain tumor may include surgical resection, chemo and radiation therapy. Survival time of this brain tumor varies - younger age and low-grade initial diagnosis are factors in improved survival time. | Even after surgery, an oligoastrocytoma will often recur. The treatment for a recurring brain tumor may include surgical resection, chemo and radiation therapy. Survival time of this brain tumor varies - younger age and low-grade initial diagnosis are factors in improved survival time. | ||
==External links== | ==External links== | ||
* [http://rad.usuhs.mil/medpix/radpix.html?mode=single&recnum=1066&th=-1 Images] | * [http://rad.usuhs.mil/medpix/radpix.html?mode=single&recnum=1066&th=-1 Images] | ||
{{Nervous tissue tumors}} | {{Nervous tissue tumors}} | ||
{{SIB}} | {{SIB}} | ||
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[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:DiseaseState]] | |||
== Acknowledgements == | == Acknowledgements == | ||
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D. | The content on this page was first contributed by: C. Michael Gibson, M.S., M.D. | ||
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[[pt:Oligoastrocitoma]] | [[pt:Oligoastrocitoma]] | ||
{{WH}} | {{WH}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 18:42, 9 January 2009
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
Oligoastrocytomas are a subset of brain tumor that present with an appearance of mixed glial cell origin, astrocytoma and oligodendroglioma. Often called a "mixed glioma", about 2.3% of all reported brain tumors are diagnosed as oligoastrocytoma. The median age of diagnosis is 42 years of age.
Oligoastrocytomas, like astrocytomas and oligodendrogliomas, can have malignant (anaplastic) histology. However, lower grades can have less aggressive biology.
Symptoms
There are many possible symptoms of oligodendrogliomas that are similar to other gliomas. These symptoms may include headache, seizure and speech or motor changes.
Diagnosis
A Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) scan is necessary to characterize the anatomy of this tumor (size, location, heter/homogeneity). However, final diagnosis of this tumor, like most tumors, relies on histopathologic examination (biopsy examination).
Treatment
If resected, the surgeon will remove as much of this tumor as possible, without disturbing eloquent regions of the brain (speech/motor cortex) and other critical brain structure. Thereafter, treatment may include chemotherapy and radiation therapy of doses and types ranging based upon the patient's needs. Subsequent MRI examination are often necessary to monitor the resection cavity.
Prognosis
Even after surgery, an oligoastrocytoma will often recur. The treatment for a recurring brain tumor may include surgical resection, chemo and radiation therapy. Survival time of this brain tumor varies - younger age and low-grade initial diagnosis are factors in improved survival time.
External links
Template:Nervous tissue tumors
Template:SIB
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.