Adult brain tumors: Difference between revisions
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Revision as of 20:59, 11 January 2009
| Adult brain tumors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editor in Chief: Cafer Zorkun, M.D., Ph.D. [2]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Classification & Grading
The WHO grading of CNS tumors establishes a malignancy scale based on histologic features of the tumor. The histologic grades are as follows:
- WHO grade I includes lesions with low proliferative potential, a frequently discrete nature, and the possibility of cure following surgical resection alone.
- WHO grade II includes lesions that are generally infiltrating and low in mitotic activity but recur. Some tumor types tend to progress to higher grades of malignancy.
- WHO grade III includes lesions with histologic evidence of malignancy, generally in the form of mitotic activity, clearly expressed infiltrative capabilities, and anaplasia.
- WHO grade IV includes lesions that are mitotically active, necrosis-prone, and generally associated with a rapid preoperative and postoperative evolution of disease.
Brain Tumors in Adult Population
Neuroepithelial tumors
Glial tumors
- Astrocytic tumors.
- Pilocytic astrocytoma.
- Diffuse astrocytoma (including fibrillary, protoplasmic, and gemistocytic).
- Anaplastic astrocytoma.
- Glioblastoma (including giant cell glioblastoma, and gliosarcoma).
- Pleomorphic xanthoastrocytoma.
- Subependymal giant cell astrocytoma.
- Oligodendroglial tumors.
- Oligodendroglioma.
- Anaplastic oligodendroglioma.
- Mixed gliomas.
- Oligoastrocytoma.
- Anaplastic oligoastrocytoma.
- Ependymal tumors.
- Myxopapillary ependymoma.
- Subependymoma.
- Ependymoma (including cellular, papillary, clear cell, and tanycytic).
- Anaplastic ependymoma.
- Neuroepithelial tumors of uncertain origin.
- Astroblastoma.
- Chordoid glioma of the third ventricle.
- Gliomatosis cerebri.
Neuronal and mixed neuronal-glial tumors (some glial component may be present)
- Gangliocytoma.
- Ganglioglioma.
- Desmoplastic infantile astrocytoma / ganglioglioma.
- Dysembryoplastic neuroepithelial tumor.
- Central neurocytoma.
- Cerebellar liponeurocytoma
- Paraganglioma.
Nonglial tumors
- Embryonal tumors.
- Ependymoblastoma.
- Medulloblastoma.
- Supratentorial primitive neuroectodermal tumor (PNET).
- Choroid plexus tumors.
- Choroid plexus papilloma.
- Choroid plexus carcinoma.
- Pineal parenchymal tumors.
- Pineoblastoma.
- Pineocytoma.
- Pineal parenchymal tumor of intermediate differentiation.
Meningeal tumors
- Meningioma.
- Hemangiopericytoma.
- Melanocytic lesion.
Germ cell tumors
- Germinoma.
- Embryonal carcinoma.
- Yolk-sac tumor (endodermal-sinus tumor).
- Choriocarcinoma.
- Teratoma.
- Mixed germ cell tumor.
Tumors of the sellar region
- Pituitary adenoma.
- Pituitary carcinoma.
- Craniopharyngioma.
Tumors of uncertain histogenesis
- Capillary hemangioblastoma.
Primary CNS lymphoma
Tumors of peripheral nerves that affect the CNS
- Schwannoma.
Metastatic tumors