The heart in progressive systemic sclerosis (scleroderma): Difference between revisions
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It's generally thought cardiac disease is a major cause of death from scleroderma, or that it often contributes to death. Conduction abnormalities, [[myocardial]] and [[pericardial disease]] disease may also be common. | It's generally thought cardiac disease is a major cause of death from scleroderma, or that it often contributes to death. Conduction abnormalities, [[myocardial]] and [[pericardial disease]] disease may also be common. | ||
An angiography-based study of 172 patients has suggested patients who may have obstructive epicardial disease associate with scleroderma should be treated the same as patients without scleroderma.<ref name="pmid16606654">{{cite journal |author=Akram MR, Handler CE, Williams M, ''et al'' |title=Angiographically proven coronary artery disease in scleroderma |journal=Rheumatology (Oxford) |volume=45 |issue=11 |pages=1395–8 |year=2006 |month=November |pmid=16606654 |doi=10.1093/rheumatology/kel120 |url=}}</ref> | |||
==Pathology== | ==Pathology== | ||
Revision as of 20:31, 11 May 2009
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Overview
Severe complications from Progressive Systemic Scleroderma (Scleroderma) can include:
- Untreated high blood pressure that strains the heart
- irregular heart rhythm
- enlargement of the heart, which leads to heart failure.
It's generally thought cardiac disease is a major cause of death from scleroderma, or that it often contributes to death. Conduction abnormalities, myocardial and pericardial disease disease may also be common.
An angiography-based study of 172 patients has suggested patients who may have obstructive epicardial disease associate with scleroderma should be treated the same as patients without scleroderma.[1]
Pathology
References